Advocating for the Prehospital Administration of Low-Titer O+ Whole Blood: Dispelling Myths and Misinformation.

Abstract

The prehospital administration of low-titer O whole blood (LTOWB) has gained attention as a lifesaving intervention in trauma care, demonstrating associated significant survival benefits over traditional crystalloid and component therapies. Despite a growing body of evidence from both military and civilian studies supporting its efficacy, safety, and feasibility, LTOWB continues to face criticism. This article examines commonly raised objections, including concerns over patient identification, blood rewarming, transfusion reactions, and potential risks for childbearing women. Emphasizing the need for transparency and evidence-based progress, this article advocates for the integration of LTOWB into prehospital protocols, positioning it as a crucial advancement in emergency medical services and trauma care.