Priya Mistry, Hannah J Leach, Elizabeth R Buse, Trevor R Smith
{"title":"Management of type 1 (acute) intestinal failure.","authors":"Priya Mistry, Hannah J Leach, Elizabeth R Buse, Trevor R Smith","doi":"10.1136/bmjgast-2025-001950","DOIUrl":null,"url":null,"abstract":"<p><p>Intestinal failure (IF) is defined as 'the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth'. Type 1 IF is short-term and often perioperative in nature. Patients are managed in a multitude of healthcare settings, particularly surgical and critical care areas. Type 1 IF can lead to malnutrition, which is prevalent in hospitals and has significant consequences for patient outcomes. Type 1 IF patients require short-term parenteral nutrition (PN) support; the provision of PN in hospitals should be managed by a multidisciplinary nutrition support team (NST).Nutritional assessment should include estimating requirements for energy, protein, fluid and electrolytes, based on basal requirements with adjustments for higher demands. All patients should be assessed for risk of refeeding syndrome and managed appropriately. Most patients can be managed using multichamber PN bags. A small minority may require bespoke PN. PN should always be provided with micronutrients and electrolytes.A central venous catheter is the preferred choice for venous access. All intravenous devices used for PN should be handled using an aseptic non-touch technique. If a catheter-related bloodstream infection is suspected, the diagnosis should be made using paired blood culture sampling.All patients should undergo ward-based and blood monitoring. The frequency of monitoring may be reduced if PN continues for a longer duration, under NST advice. Daily assessment should also include monitoring for signs of resolution of IF, and the introduction of oral/enteral nutrition.</p>","PeriodicalId":9235,"journal":{"name":"BMJ Open Gastroenterology","volume":"12 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMJ Open Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/bmjgast-2025-001950","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Intestinal failure (IF) is defined as 'the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth'. Type 1 IF is short-term and often perioperative in nature. Patients are managed in a multitude of healthcare settings, particularly surgical and critical care areas. Type 1 IF can lead to malnutrition, which is prevalent in hospitals and has significant consequences for patient outcomes. Type 1 IF patients require short-term parenteral nutrition (PN) support; the provision of PN in hospitals should be managed by a multidisciplinary nutrition support team (NST).Nutritional assessment should include estimating requirements for energy, protein, fluid and electrolytes, based on basal requirements with adjustments for higher demands. All patients should be assessed for risk of refeeding syndrome and managed appropriately. Most patients can be managed using multichamber PN bags. A small minority may require bespoke PN. PN should always be provided with micronutrients and electrolytes.A central venous catheter is the preferred choice for venous access. All intravenous devices used for PN should be handled using an aseptic non-touch technique. If a catheter-related bloodstream infection is suspected, the diagnosis should be made using paired blood culture sampling.All patients should undergo ward-based and blood monitoring. The frequency of monitoring may be reduced if PN continues for a longer duration, under NST advice. Daily assessment should also include monitoring for signs of resolution of IF, and the introduction of oral/enteral nutrition.
期刊介绍:
BMJ Open Gastroenterology is an online-only, peer-reviewed, open access gastroenterology journal, dedicated to publishing high-quality medical research from all disciplines and therapeutic areas of gastroenterology. It is the open access companion journal of Gut and is co-owned by the British Society of Gastroenterology. The journal publishes all research study types, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Publishing procedures are built around continuous publication, publishing research online as soon as the article is ready.