Insights into the molecular mechanism of neurological diseases and their pathophysiological responses

Abstract

The origin of neurological disorders and their associated symptoms have been known for a very long time tracing to the origin of human being. However, the detailed mechanism at the molecular level came to existence after intensive research for decades. This review aims to discuss the molecular mechanisms responsible for the onset till the progression of these diseases casting its role at cellular, organelles, and metal ions level. Advanced microscopic techniques enabled correlation of pathological responses at ultrastructural level that is helpful if coupled with biochemical parameters. The review also sheds a glimpse of focus on creative movements to improve cognition in neurodegenerative patients as a part of therapy.