Outpatient continuous adductor canal block (CACB) for total knee arthroplasty: a double-blinded randomized placebo-controlled trial.

IF 3.5 2区 医学 Q1 ANESTHESIOLOGY
Yehoshua Gleicher, Hermann Dos Santos Fernandes, Sharon Peacock, Christine Ma, Fernanda Septimio Lanza Oliveira, Divya Mahajan, Carlson Asanghanwa, David Carrasco Guariento, Javiera Vargas, Jesse Wolfstadt, Miki Peer, Xiang Y Ye, Naveed Siddiqui
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引用次数: 0

Abstract

Background: Total knee arthroplasty (TKA) is a widely performed procedure, with postoperative pain presenting as a major barrier to early mobilization and patient satisfaction. While single-injection adductor canal blocks (SACB) offer effective short-term analgesia, their limited duration often leads to rebound pain. Continuous adductor canal blocks (CACB) extend analgesic effects but are underexplored in outpatient settings. The objective of this study is to assess whether CACB improves quality of recovery and analgesia, in comparison to SACB in an outpatient or short-stay setting for TKA patients.

Methods: Double-blind randomized controlled trial comparing the Quality of Recovery-15 (QoR-15) score on postoperative day (POD) 2 (primary outcome) and opioid consumption, pain scores, hospital length-of-stay, and complications (secondary outcomes), between patients receiving CACB and SACB, when undergoing primary TKA.

Results: 60 patients were enrolled and randomized to two treatment groups: CACB (30) and SACB (30). Patients in the CACB group had significantly higher QoR-15 scores at PODs 1 (128.83±12.36 vs 109.00±15.90, p<0.001), 2 (131.27±10.23 vs 110.86±15.37, p<0.001) and 3 (131.97±13.94 vs 111.18±18.28, p<0.001). They also had lower opioid consumption and pain scores at rest and with movement during the first three PODs. No major complications or signs of local anesthetic systemic toxicity were observed.

Conclusions: In our study, CACB significantly enhanced early postoperative recovery and analgesia following TKA in an outpatient or short-stay setting, compared with SACB, and these results support its broader adoption in fast-track TKA pathways.

门诊连续内收管阻滞(CACB)用于全膝关节置换术:一项双盲随机安慰剂对照试验。
背景:全膝关节置换术(TKA)是一种广泛应用的手术,术后疼痛是早期活动和患者满意度的主要障碍。虽然单次注射内收管阻滞(SACB)可以提供有效的短期镇痛,但其持续时间有限,经常导致反跳疼痛。连续内收管阻滞(CACB)扩大镇痛效果,但在门诊设置未充分探索。本研究的目的是评估与SACB相比,在门诊或短期住院的TKA患者中,CACB是否提高了恢复和镇痛的质量。方法:双盲随机对照试验,比较CACB和SACB患者在接受原发性TKA时术后一天(POD) 2(主要结局)和阿片类药物消耗、疼痛评分、住院时间和并发症(次要结局)的恢复质量-15 (QoR-15)评分。结果:60例患者入组,随机分为CACB组(30例)和SACB组(30例)。在我们的研究中,与SACB相比,CACB组患者在pod 1时的QoR-15评分明显更高(128.83±12.36 vs 109.00±15.90)。结论:在我们的研究中,与SACB相比,CACB显著增强了门诊或短期住院TKA后的早期术后恢复和镇痛,这些结果支持其在快速通道TKA途径中的广泛采用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.50
自引率
11.80%
发文量
175
审稿时长
6-12 weeks
期刊介绍: Regional Anesthesia & Pain Medicine, the official publication of the American Society of Regional Anesthesia and Pain Medicine (ASRA), is a monthly journal that publishes peer-reviewed scientific and clinical studies to advance the understanding and clinical application of regional techniques for surgical anesthesia and postoperative analgesia. Coverage includes intraoperative regional techniques, perioperative pain, chronic pain, obstetric anesthesia, pediatric anesthesia, outcome studies, and complications. Published for over thirty years, this respected journal also serves as the official publication of the European Society of Regional Anaesthesia and Pain Therapy (ESRA), the Asian and Oceanic Society of Regional Anesthesia (AOSRA), the Latin American Society of Regional Anesthesia (LASRA), the African Society for Regional Anesthesia (AFSRA), and the Academy of Regional Anaesthesia of India (AORA).
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