Gastrojejunostomy revision combined with biliopancreatic limb lengthening provides superior weight loss and metabolic outcomes compared to gastrojejunostomy revision alone in Roux-en-Y gastric bypass patients with weight recurrence.

IF 2.7 2区 医学 Q2 SURGERY
Leo I Amodu, Lauren Johnson, Kallie E Wynens, Omkar S Pawar, Nicholas Catanzaro, Sakib Adnan, Leena Khaitan, Mujjahid Abbas
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引用次数: 0

Abstract

Introduction: The Roux-en-Y gastric bypass (RNYGB) is an effective bariatric surgical procedure for weight loss. Some patients experience weight recurrence or fail to lose weight after a RNYGB. No consensus exists on a recommended revisional procedure for RNYGB patients with weight recurrence.

Methods: We carried out a retrospective review of records from 2010 to 2024, examining patients who had a prior RNYGB, requiring revision for weight recurrence. We compared patients who had revision of the gastrojejunal (GJ) anastomosis alone, to patients who had revision of the gastrojejunal anastomosis and lengthening of the biliopancreatic (BP) limb (GJ + BPLL). We compared demographics, weight outcomes, as well as postoperative complications.

Results: Fifty-one RNYGB patients had a revision primarily for weight recurrence. Twenty-three patients had a GJ revision alone, while 28 patients had a GJ + BPLL. At 24 months post-revision, the GJ + BPLL group had a significantly lower median weight (lbs.) (GJ vs. GJ + BPLL; 288 vs. 186, p = 0.003), as well as BMI (GJ vs. GJ + BPLL; 45.1 vs. 31.91, p = 0.024). Post-revision HbA1c levels were also significantly lower in the GJ + BPLL group (GJ vs. GJ + BPLL; 5.4 vs. 5, p = 0.035). The GJ + BPLL group had a higher rate of multiple vitamin deficiencies. There was no difference between the groups beyond 36 months.

Conclusion: In patients with weight recidivism after a primary RNYGB, GJ + BPLL can achieve greater reduction in weight and BMI with comparable complication rates compared to GJ revision alone, with a clear advantage in HbA1c reduction. While the weight loss outcomes appear to equalize between groups after 36 months, no patients with GJ + BPLL returned to their pre-revision weight. Larger studies are needed to evaluate differences in durability of GJ + BPLL, as well as other long-term outcomes.

在体重复发的Roux-en-Y胃分流术患者中,与单独进行胃空肠吻合术相比,胃空肠吻合术改良联合胆胰肢体延长提供了更好的体重减轻和代谢结果。
Roux-en-Y胃旁路术(RNYGB)是一种有效的减肥手术。一些患者在RNYGB后体重复发或未能减轻。对于体重复发的RNYGB患者的推荐修正程序尚无共识。方法:我们对2010年至2024年的记录进行了回顾性研究,检查了先前有RNYGB,需要体重复发的患者。我们比较了仅行胃空肠(GJ)吻合术翻修的患者与行胃空肠吻合术翻修并延长胆胰(BP)肢(GJ + BPLL)的患者。我们比较了人口统计学、体重结果以及术后并发症。结果:51例RNYGB患者主要因体重复发而进行了翻修。23例患者仅行GJ翻修,28例患者行GJ + BPLL。改良后24个月,GJ + BPLL组的中位体重(磅)显著降低。(GJ vs. GJ + BPLL; 288 vs. 186, p = 0.003), BMI (GJ vs. GJ + BPLL; 45.1 vs. 31.91, p = 0.024)。改良后HbA1c水平在GJ + BPLL组也显著降低(GJ vs. GJ + BPLL; 5.4 vs. 5, p = 0.035)。GJ + BPLL组多种维生素缺乏率较高。超过36个月,两组之间没有差异。结论:在原发性RNYGB术后体重再犯的患者中,GJ + BPLL与单独GJ改良相比,可以实现更大的体重和BMI的降低,并发症发生率相当,在降低HbA1c方面具有明显优势。虽然36个月后各组之间的体重减轻结果似乎相等,但GJ + BPLL患者没有恢复到翻修前的体重。需要更大规模的研究来评估GJ + BPLL的持久性差异,以及其他长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
12.90%
发文量
890
审稿时长
6 months
期刊介绍: Uniquely positioned at the interface between various medical and surgical disciplines, Surgical Endoscopy serves as a focal point for the international surgical community to exchange information on practice, theory, and research. Topics covered in the journal include: -Surgical aspects of: Interventional endoscopy, Ultrasound, Other techniques in the fields of gastroenterology, obstetrics, gynecology, and urology, -Gastroenterologic surgery -Thoracic surgery -Traumatic surgery -Orthopedic surgery -Pediatric surgery
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