Bimodal ECG and PCG Cardiovascular Disease Detection: Exploring the Potential and Modality Contribution.

IF 5.7 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES
Alessia Calzoni, Mattia Savardi, Marco Silvestri, Sergio Benini, Alberto Signoroni
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引用次数: 0

Abstract

Early detection of cardiovascular diseases (CVDs) is crucial for improving patient outcomes and alleviating healthcare burdens. Electrocardiograms (ECGs) and phonocardiograms (PCGs) offer low-cost, non-invasive, and easily integrable solutions for preventive care settings. In this work, we propose a novel bimodal deep learning model that combines ECG and PCG signals to enhance the early detection of CVDs. To address the challenge of limited bimodal data, we fine-tuned a Convolutional Neural Network (CNN) pre-trained on large-scale audio recordings, leveraging all publicly available unimodal PCG datasets. This PCG branch was then integrated with a 1D-CNN ECG branch via late fusion. Evaluated on an augmented version of MITHSDB, currently the only publicly available bimodal dataset, our approach achieved an AUROC of 96.4%, significantly outperforming ECG-only and PCG-only models by approximately 3%pts and 11%pts, respectively. To interpret the model's decisions, we applied three explainability techniques, quantifying the relative contributions of the electrical and acoustic features. Furthermore, by projecting the learned embeddings into two dimensions using UMAP, we revealed clear separation between normal and pathological samples. Our results conclusively demonstrate that combining ECG and PCG modalities yields substantial performance gains, with explainability and visualization providing critical insights into model behavior. These findings underscore the importance of multimodal approaches for CVDs diagnosis and prevention, and strongly motivate the collection of larger, more diverse bimodal datasets for future research.

Abstract Image

Abstract Image

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双峰心电图和PCG心血管疾病检测:探索潜力和模式贡献。
心血管疾病(cvd)的早期检测对于改善患者预后和减轻医疗负担至关重要。心电图(ECGs)和心音图(PCGs)为预防保健设置提供低成本、无创和易于集成的解决方案。在这项工作中,我们提出了一种新的双峰深度学习模型,该模型结合了ECG和PCG信号来增强cvd的早期检测。为了解决有限的双峰数据的挑战,我们对卷积神经网络(CNN)进行了微调,利用所有公开可用的单峰PCG数据集,对大规模录音进行了预训练。然后通过后期融合将该PCG分支与1D-CNN ECG分支整合。在MITHSDB的增强版本(目前唯一公开可用的双峰数据集)上进行评估,我们的方法实现了96.4%的AUROC,显著优于仅ecg和仅pcg模型,分别约为3%和11%。为了解释模型的决定,我们应用了三种可解释性技术,量化了电和声学特征的相对贡献。此外,通过使用UMAP将学习到的嵌入投影到两个维度,我们揭示了正常和病理样本之间的明确区分。我们的研究结果最终证明,结合ECG和PCG模式可以显著提高性能,可解释性和可视化提供了对模型行为的关键见解。这些发现强调了多模态方法对心血管疾病诊断和预防的重要性,并强烈鼓励为未来的研究收集更大、更多样化的双模态数据集。
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来源期刊
Journal of Medical Systems
Journal of Medical Systems 医学-卫生保健
CiteScore
11.60
自引率
1.90%
发文量
83
审稿时长
4.8 months
期刊介绍: Journal of Medical Systems provides a forum for the presentation and discussion of the increasingly extensive applications of new systems techniques and methods in hospital clinic and physician''s office administration; pathology radiology and pharmaceutical delivery systems; medical records storage and retrieval; and ancillary patient-support systems. The journal publishes informative articles essays and studies across the entire scale of medical systems from large hospital programs to novel small-scale medical services. Education is an integral part of this amalgamation of sciences and selected articles are published in this area. Since existing medical systems are constantly being modified to fit particular circumstances and to solve specific problems the journal includes a special section devoted to status reports on current installations.
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