Brugada ECG Pattern in A Caucasian Patient with Severe Hypothyroidism.

Q3 Medicine
European journal of case reports in internal medicine Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI:10.12890/2025_005544
Erminia De Cristofaro, Maria Giulia Canè, Davide Cunzi, Giorgia Prampolini, Silvia Daniela Umbertina Fedeli, Aurelio Negro
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引用次数: 0

Abstract

Brugada syndrome (BrS) is a disorder leading to potentially life-threatening ventricular arrhythmias in patients with an apparently normal heart. It mostly affects men of Asian descent, and the prevalence varies between ethnicities. Typical ECG abnormalities with no symptoms are referred to as the Brugada pattern, and hypothyroidism is a potential trigger of this. We report on a Caucasian man with severe hypothyroidism and Brugada ECG pattern, which normalised after starting replacement therapy. The association has been previously described in only a few patients.

Learning points: Brugada syndrome (BrS) is a potentially life-threatening disease that can be easily recognized on the electrocardiogram (ECG). Typical ECG abnormalities associated with no clinical symptoms is referred to as the Brugada pattern.Many studies have underscored the association between hypothyroidism and Brugada ECG pattern, that can be reversed by a prompt initiation of replacement therapy.

Abstract Image

Abstract Image

1例白种人严重甲状腺功能减退症的Brugada心电图模式。
Brugada综合征(BrS)是一种在表面正常的心脏患者中导致潜在危及生命的室性心律失常的疾病。它主要影响亚裔男性,不同种族的患病率有所不同。无症状的典型心电图异常称为Brugada型,甲状腺功能减退是其潜在诱因。我们报告了一位患有严重甲状腺功能减退和Brugada心电图模式的高加索男性,在开始替代治疗后恢复正常。这种关联以前只在少数患者中被描述过。学习要点:Brugada综合征(BrS)是一种潜在的危及生命的疾病,可以很容易地在心电图(ECG)上识别出来。无临床症状的典型心电图异常称为Brugada型。许多研究强调了甲状腺功能减退和Brugada心电图模式之间的联系,这种联系可以通过迅速开始替代治疗来逆转。
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来源期刊
CiteScore
2.10
自引率
0.00%
发文量
166
审稿时长
8 weeks
期刊介绍: The European Journal of Case Reports in Internal Medicine is an official journal of the European Federation of Internal Medicine (EFIM), representing 35 national societies from 33 European countries. The Journal''s mission is to promote the best medical practice and innovation in the field of acute and general medicine. It also provides a forum for internal medicine doctors where they can share new approaches with the aim of improving diagnostic and clinical skills in this field. EJCRIM welcomes high-quality case reports describing unusual or complex cases that an internist may encounter in everyday practice. The cases should either demonstrate the appropriateness of a diagnostic/therapeutic approach, describe a new procedure or maneuver, or show unusual manifestations of a disease or unexpected reactions. The Journal only accepts and publishes those case reports whose learning points provide new insight and/or contribute to advancing medical knowledge both in terms of diagnostics and therapeutic approaches. Case reports of medical errors, therefore, are also welcome as long as they provide innovative measures on how to prevent them in the current practice (Instructive Errors). The Journal may also consider brief and reasoned reports on issues relevant to the practice of Internal Medicine, as well as Abstracts submitted to the scientific meetings of acknowledged medical societies.
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