Evaluating the predictive accuracy of cognitive screeners BAMCOG and MoCA in identifying postoperative delirium risk in aortic valve replacement patients: A cohort study.

IF 7.7
PLOS digital health Pub Date : 2025-09-08 eCollection Date: 2025-09-01 DOI:10.1371/journal.pdig.0001005
Mariska E Te Pas, Sophie Adelaars, R Arthur Bouwman, Roy P C Kessels, Marcel G M Olde Rikkert, Daan van de Kerkhof, Erwin Oosterbos, Marc P Buise
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Abstract

Postoperative delirium (POD) and postoperative encephalopathy (POE) are common complications in older adults undergoing aortic valve replacement (AVR), yet the predictive accuracy of cognitive screening tools remains uncertain. In this prospective cohort study, 50 patients aged 65 years and older scheduled for AVR between January and October 2022 underwent preoperative assessment with the Brain Aging Monitor Cognitive Assessment (BAMCOG) and Montreal Cognitive Assessment (MoCA). Postoperatively, POD was evaluated with the Delirium Observation Screening (DOS) scale and POE with electroencephalography (EEG). BAMCOG and MoCA showed poor accuracy in predicting POE, with AUROC values of 0.67 and 0.59 respectively, but BAMCOG demonstrated good accuracy for POD prediction (AUROC 0.85) compared with MoCA (AUROC 0.53). Higher BAMCOG scores were significantly associated with reduced POD incidence, with each 10% increase in score lowering the risk by 16%. These findings suggest that BAMCOG may be a valuable preoperative screening tool for POD, though larger studies are needed to confirm its clinical utility and establish optimal cutoff values.

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评估认知筛查器BAMCOG和MoCA对主动脉瓣置换术患者术后谵妄风险的预测准确性:一项队列研究。
术后谵妄(POD)和术后脑病(POE)是接受主动脉瓣置换术(AVR)的老年人的常见并发症,但认知筛查工具的预测准确性仍不确定。在这项前瞻性队列研究中,50名65岁及以上的AVR患者在2022年1月至10月期间接受了脑老化监测认知评估(BAMCOG)和蒙特利尔认知评估(MoCA)的术前评估。术后用谵妄观察筛查(DOS)量表评估POD,用脑电图(EEG)评估POE。BAMCOG和MoCA预测POE的准确度较差,AUROC分别为0.67和0.59,而BAMCOG预测POD的准确度为0.85,高于MoCA (AUROC为0.53)。较高的BAMCOG评分与POD发生率降低显著相关,评分每增加10%,风险降低16%。这些发现表明BAMCOG可能是一种有价值的POD术前筛查工具,尽管需要更大规模的研究来证实其临床应用并建立最佳临界值。
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