10-(4-Fluorophenyl)-4-[(4-fluorophenyl)amino]-5-phenyl-5,8,9,10-tetrahydropyrimido[4,5-b]quinolin-6(7H)-one

IUCrData Pub Date : 2025-08-01 DOI:10.1107/S2414314625007047

Sizwe J. Zamisa , Adesola A. Adeleke , Bernard Omondi

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Abstract

The title compound forms a crystal structure with near-coplanar heteroaryl units and perpendicular aromatic rings, assembling into a corrugated two-dimensional network along the crystallographic ac plane that is consolidated into a three-dimensional supramolecular architecture via hydrogen bonding.

The asymmetric unit of the title compound, C₂₉H₂₂F₂N₄O, consists of one molecule in which the pyrimidinyl and anilinyl units exhibit near coplanarity, subtending a dihedral angle of 10.22 (7)°. In contrast, the dihydropyridine and phenyl rings are nearly perpendicular, making angles of 88.66 (7) and 89.14 (7)°. The crystal packing features alternating C—H⋯π and C—F⋯π interactions that generate a corrugated two-dimensional supramolecular network in the crystallographic ac plane. This structure is further consolidated into a three-dimensional architecture by C—H⋯F hydrogen bonding.

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(10) - 4-Fluoro-phen-yl 4 - [(4-Fluoro-phen-yl)氨基]5-phenyl-5, 8, 9, 10-tetra-hydro-pyrimido(4、5 b) quin-olin-6——(7 h)。

标题化合物c29h22f2n40o的不对称单元由一个分子组成，其中嘧啶基和苯胺基单元呈近共平面，其二面角为10.22(7)°。二氢吡啶环与苯基环几乎垂直，成88.66(7)°和89.14(7)°角。晶体填料具有交替的C-H⋯π和C-F⋯π相互作用，在晶体学ac平面上产生波纹状的二维超分子网络。这种结构通过C-H⋯F氢键进一步巩固成三维结构。

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