Effects of Virtual Reality-guided Imagery Relaxation Intervention in Improving Anxiety Among Lung Cancer Patients: A Randomized Controlled Trial

IF 2.9 3区医学 Q2 NURSING

Asian Nursing Research Pub Date : 2025-12-01 Epub Date: 2025-09-05 DOI:10.1016/j.anr.2025.08.003

Huiqin Li, Fengxia Liu, Shujun Li, Chuang Li, Ziqiang Tian

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引用次数: 0

Abstract

Purpose

To examine the effectiveness of virtual reality-guided imagery relaxation (VRGI) intervention in reducing anxiety among lung cancer surgery patients.

Methods

In a randomized clinical trial, 98 patients were assigned to a control group (CG) receiving routine treatment and staged care in thoracic surgery, or an experimental group (EG) receiving additional VRGI in addition to the CG’s protocol. Anxiety (using the State-Trait Anxiety Inventory) and physiological stress markers [systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR)] were assessed on the day of admission (T1), immediately before surgery (T2), and at discharge (T3).

Results

A total of 98 participants were recruited and randomized to the CG (n=53) and EG (n=45). The age [β, 6.29; p = .005], education level (β, 5.57; p = .011), awareness of the disease (β, 6.11; p = .007), and gender (β, 5.75; p = .018) were the major influencing factors of preoperative anxiety. Compared with the CG, the EG showed a smaller increase in State Anxiety Inventory (SAI, t = 2.20; p = .003), SBP (t = 2.75; p = .007), DBP (t = 2.53; p = .013), and HR (t = 2.17; p = .033) at T2, and significant decreases in SAI (t = 4.79; p < .001), SBP (t = 3.25; p = .0027), DBP (t = 2.96; p = .004), and HR (t = 4.26; p < .001) at T3. The results of the repeated measures ANOVA demonstrated statistically significant differences in the SAI score, SBP, DBP, and HR across time effect, group effect and time × group interaction effect (p < .05), with the EG exhibited superior outcomes.

Conclusion

VRGI is a feasible and effective intervention for reducing perioperative anxiety and physiological stress in lung cancer surgery patients, warranting further large-scale trials.

Trial registration

This study is retrospectively registered with the ITMCTR (identifier: ITMCTR2025001481, registered 26 July 2025). http://itmctr.ccebtcm.org.cn/zh-CN/UserPlatform/ProjectView?Pid=48c26a67-4e2b-4aea-a504-f379602513b0.

查看原文本刊更多论文

虚拟现实引导的图像放松干预对改善肺癌患者焦虑的影响：一项随机对照试验。

目的：探讨虚拟现实（VR）引导下的影像放松（VRGI）干预对降低肺癌手术患者焦虑的效果。方法：在河北医科大学第四附属医院（中国河北石家庄）进行一项随机临床试验，招募计划于2023年12月至2024年3月在全身麻醉下进行首次择期内镜肺癌手术的患者。患者按1:1的比例随机分为对照组和实验组，对照组接受胸外科常规治疗和分阶段护理，实验组在对照组方案的基础上接受VRGI干预。主要结果是焦虑评估的状态-特质焦虑量表（STAI）得分。次要结局包括生理应激指标的改变（收缩压[SBP]、舒张压[DBP]和心率[HR]）。在入院当天（T1）、手术前（T2）和出院时（T3） 3个时间点评估结果。采用重复测量方差分析（ANOVA）来比较结果随时间的变化。结果：共纳入98例受试者（M [QIR]年龄60.00[54.25,68.00]岁，男性39例[39.8%]，女性59例[60.2%]），随机分为对照组53例和实验组45例。年龄（β, 6.29, 95%CI, 2.09 ~ 10.69， P= 0.005）、文化程度（β, -5.57, 95%CI, -9.76 ~ -1.37， P= 0.011）、疾病认知（β, 6.11, 95%CI, 1.80 ~ 10.62， P= 0.007）、性别（β, 5.75, 95%CI, 1.09 ~ 10.40， P= 0.018）是术前焦虑的主要影响因素。与对照组相比，VRGI试验组T2时SAI （t=2.20， P= 0.003）、收缩压（t=2.75， P= 0.007）、DBP （t=2.53， P= 0.013）和HR （t=2.17， P= 0.033）的升高幅度更小，而SAI （t= 4.79, P < 0.001）、SBP （t=3.25， P= 0.0027）、DBP （t=2.96， P= 0.004）和HR （t=4.26， P= 0.05）的升高幅度更大。结论：VRGI是减少肺癌择期内镜手术患者焦虑的一种可行、有效的方法。此外，它还显示出减轻生理应激反应和增强患者自信心的潜力。本研究中观察到的积极结果表明，需要进行大规模、多中心随机对照试验来证实干预措施在不同临床人群中的有效性。试验注册：本研究在ITMCTR回顾性注册（标识符：ITMCTR2025001481，注册日期为2025年7月26日）。http://itmctr.ccebtcm.org.cn/zh-CN/UserPlatform/ProjectView?Pid=48c26a67-4e2b-4aea-a504-f379602513b0。

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来源期刊

Asian Nursing Research NURSING-

CiteScore

4.20

自引率

4.50%

发文量

审稿时长

45 days

期刊介绍： Asian Nursing Research is the official peer-reviewed research journal of the Korean Society of Nursing Science, and is devoted to publication of a wide range of research that will contribute to the body of nursing science and inform the practice of nursing, nursing education, administration, and history, on health issues relevant to nursing, and on the testing of research findings in practice.