Response to the Letter to the Editor regarding “Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study”
Anna Josefsson, Michael Axenhus, Raéd Itayem, Sebastian Mukka, Martin Magnéli
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引用次数: 0
Abstract
We appreciate the interest shown by Drs. Wahl and Gautier in our recent publication and thank them for their thoughtful comments and critical reading of our work.
We acknowledge the inversion of colours in Figure 1 and appreciate the authors' attention to this detail. We agree that a corrigendum should be issued to clarify that the orange curve corresponds to the polished tapered stem (PTS) and the blue curve to the anatomical stem (AS).
The concern raised about potential confounding due to surgical technique is valid and warrants discussion. However, we respectfully disagree that intraoperative errors or technical shortcomings primarily explain our findings. First, our study was conducted at a single high-volume university-affiliated centre, where both stem types were implanted by experienced orthopaedic surgeons using standardised protocols. Importantly, the transition from PTS to AS was a deliberate department-wide change, accompanied by training to ensure continuity and consistency of technique. Second, while the pattern of early periprosthetic fractures in the PTS group may resemble that seen with uncemented stems, this pattern is consistent with prior literature reporting higher early PFF rates in force-closed polished tapered designs in frail populations. These findings have been replicated in multiple registry studies and observational cohorts, and our study adds mid-term follow-up confirmation to this established trend. Third, the suggestion that aggressive broaching or specific technical challenges contributed to early PFFs is mainly speculative. Both stem designs were implanted in patients with similar baseline characteristics, and the transition was not associated with any significant increase in complications during the learning curve period.
We note the concern about the higher observed PJI rate in the PTS group. While the PJI rate exceeded 1% in both groups, it remained within the expected range for a frail hip fracture population with advanced age and comorbidities. Notably, the AS group had a lower PJI and dislocation rate despite the potential for surgical adaptation during the transition, supporting the robustness of the findings.
We agree that our findings should not be extrapolated to all force-closed stems, nor to other settings without careful consideration. Our conclusions are based on the specific stem models used and the population studied. However, as others have shown, including the registry study cited by Drs. Wahl and Gautier, CPT stems have been associated with a higher fracture risk than their Exeter counterparts, underscoring the importance of implant selection even within design classes.
We welcome this opportunity to further clarify our findings and reiterate that while surgical technique is always important, the evidence in our study supports the conclusion that stem design plays a critical role in the risk of periprosthetic fracture.
Sincerely,
Anna Josefsson, Michael Axenhus, Raéd Itayem, Sebastian Mukka, Martin Magnéli (On behalf of all authors).
我们感谢博士们对我们的关心。Wahl和Gautier在我们最近的出版物中,感谢他们对我们工作的周到评论和批判性阅读。我们承认图1中的颜色反转,并感谢作者对这一细节的关注。我们同意应该发布一份勘误,以澄清橙色曲线对应于抛光锥形茎(PTS),蓝色曲线对应于解剖茎(AS)。由于手术技术而引起的潜在混淆的担忧是有效的,值得讨论。然而,我们不同意术中错误或技术缺陷是我们发现的主要原因。首先,我们的研究是在一个单一的大容量大学附属中心进行的,在那里,两种干细胞类型都是由经验丰富的骨科医生使用标准化方案植入的。重要的是,从PTS到AS的转变是一个经过深思熟虑的全部门变革,伴随着培训以确保技术的连续性和一致性。其次,尽管PTS组早期假体周围骨折的模式可能与未骨水泥支架相似,但这一模式与先前文献报道的在体弱人群中采用力封闭抛光锥形设计的早期PFF率较高一致。这些发现在多个注册研究和观察队列中得到了重复,我们的研究为这一既定趋势增加了中期随访证实。第三,积极拉削或特定技术挑战导致早期pff的建议主要是推测性的。两种干细胞设计都植入具有相似基线特征的患者,并且在学习曲线期间过渡与并发症的任何显著增加无关。我们注意到对PTS组观察到的较高PJI率的关注。虽然PJI率在两组中均超过1%,但对于高龄和合并症的脆性髋部骨折人群,PJI率仍在预期范围内。值得注意的是,AS组的PJI和脱位率较低,尽管在过渡期间有可能进行手术适应,这支持了研究结果的稳健性。我们同意,我们的发现不应该被外推到所有的力闭系统,也不应该在没有仔细考虑的情况下推广到其他设置。我们的结论是基于所使用的特定干细胞模型和所研究的人群。然而,正如其他人所显示的,包括dr。Wahl和Gautier, CPT假体与Exeter假体相比有更高的骨折风险,这强调了即使在设计类别中选择植入物的重要性。我们很高兴有机会进一步澄清我们的发现,并重申尽管手术技术总是很重要,但我们研究中的证据支持这样的结论,即柄设计在假体周围骨折的风险中起着关键作用。真诚地,Anna Josefsson, Michael axenus, rasamad Itayem, Sebastian Mukka, Martin magn害害物(代表所有作者)。