Optimizing Laser Therapy: Efficacy and Safety of Picosecond 1,064 nm Nd:YAG Laser in Xanthelasma Palpebrarum Treatment

IF 3.4 4区医学 Q1 DERMATOLOGY

Dermatologic Therapy Pub Date : 2025-09-07 DOI:10.1155/dth/6693871

Fei Su, Luoyao Yang, Qinsi Huang, Jun Zhang, Hui Su, Yue Wang, Liuqing Chen

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引用次数: 0

Abstract

Background: Xanthelasma palpebrarum (XP) currently lacks a universally endorsed treatment approach. The utility of picosecond 1064 nm Nd:YAG lasers in XP management has not been explored.

Objective: This study aimed to assess the efficacy and safety of picosecond 1064 nm Nd:YAG laser therapy in the treatment of XP.

Methods: A total of 47 patients with clinically confirmed XP received treatment with picosecond 1064 nm Nd:YAG laser at standardized settings. Patients were photographed using standardized photographic documentation, and the degree of clearance was evaluated.

Results: Following the initial treatment session, 97.87% of patients exhibited a good response to the picosecond laser, with some degree of lesion clearance. By the third session, 78.80% of patients achieved > 50% lesion clearance. Adverse effects were mild and transient, with postinflammatory hyperpigmentation observed in 2 (4.25%) patients.

Conclusion: The picosecond 1064 nm Nd:YAG laser demonstrated promising efficacy in the treatment of XP, with a potentially enhanced safety profile.

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优化激光治疗：皮秒1064 nm Nd:YAG激光治疗palpebrarma的疗效和安全性

背景：黄斑病（XP）目前缺乏普遍认可的治疗方法。皮秒1064nm Nd:YAG激光器在XP管理中的应用尚未被探索。目的：评价皮秒1064 nm Nd:YAG激光治疗XP的疗效和安全性。方法：对47例临床确诊的XP患者进行皮秒1064 nm Nd:YAG激光治疗。使用标准化的摄影文件对患者进行拍照，并评估清除程度。结果：初始治疗后，97.87%的患者对皮秒激光有良好的反应，病变有一定程度的清除。到第三期，78.80%的患者病变清除率达到50%。不良反应轻微且短暂，2例（4.25%）患者出现炎症后色素沉着。结论：皮秒1064 nm Nd:YAG激光治疗XP具有良好的疗效，并具有潜在的安全性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatologic Therapy 医学-皮肤病学

CiteScore

7.00

自引率

8.30%

发文量

711

审稿时长

3 months

期刊介绍： Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.