Established dietary interventions and time-restricted eating for cardiovascular disease prevention.

IF 10.6 1区医学 Q1 CELL BIOLOGY

Cell Reports Medicine Pub Date : 2025-09-16 Epub Date: 2025-09-03 DOI:10.1016/j.xcrm.2025.102326

You Jin Chang, Leonie K Heilbronn, Amy T Hutchison

引用次数: 0

Abstract

Obesity and its associated metabolic disturbances, including insulin resistance, inflammation, hypertension, dyslipidemia, and plaque progression, are key drivers of cardiovascular risk. Established dietary strategies, such as the Mediterranean diet, Dietary Approaches to Stop Hypertension (DASH), and calorie restriction (CR), play a crucial role in preventing and slowing the progression of cardiovascular diseases (CVDs). Time-restricted eating (TRE) is a form of intermittent fasting where food intake is limited to 6-10 h daily, typically during daytime hours, and is showing potential to improve cardiovascular health. This review examines the evidence for and mechanisms underlying established dietary strategies and TRE in improving cardiovascular outcomes, and it explores whether incorporating established dietary interventions alongside TRE could provide synergistic cardiovascular benefits.

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建立饮食干预和限时饮食预防心血管疾病。

肥胖及其相关的代谢紊乱，包括胰岛素抵抗、炎症、高血压、血脂异常和斑块进展，是心血管风险的关键驱动因素。既定的饮食策略，如地中海饮食、停止高血压的饮食方法（DASH）和卡路里限制（CR），在预防和减缓心血管疾病（cvd）的进展方面发挥着至关重要的作用。限时饮食（TRE）是一种间歇性禁食的形式，每天的食物摄入量限制在6-10小时，通常是在白天，并且显示出改善心血管健康的潜力。本综述研究了现有饮食策略和TRE改善心血管结局的证据和机制，并探讨了将现有饮食干预与TRE结合是否可以提供协同心血管益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Reports Medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

15.00

自引率

1.40%

发文量

231

审稿时长

40 days

期刊介绍： Cell Reports Medicine is an esteemed open-access journal by Cell Press that publishes groundbreaking research in translational and clinical biomedical sciences, influencing human health and medicine. Our journal ensures wide visibility and accessibility, reaching scientists and clinicians across various medical disciplines. We publish original research that spans from intriguing human biology concepts to all aspects of clinical work. We encourage submissions that introduce innovative ideas, forging new paths in clinical research and practice. We also welcome studies that provide vital information, enhancing our understanding of current standards of care in diagnosis, treatment, and prognosis. This encompasses translational studies, clinical trials (including long-term follow-ups), genomics, biomarker discovery, and technological advancements that contribute to diagnostics, treatment, and healthcare. Additionally, studies based on vertebrate model organisms are within the scope of the journal, as long as they directly relate to human health and disease.