Dopamine as a teaching signal: understanding its role in shaping individual behavior

IF 52.7 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Seung Chan Kim, Sehwan Kim, Sang Ryong Kim
{"title":"Dopamine as a teaching signal: understanding its role in shaping individual behavior","authors":"Seung Chan Kim, Sehwan Kim, Sang Ryong Kim","doi":"10.1038/s41392-025-02406-5","DOIUrl":null,"url":null,"abstract":"<p>In a recent publication in <i>Cell</i>, Liebana and colleagues demonstrate that dopamine acts as a circuit-specific teaching signal, shaping individual learning trajectories over time. These reward prediction error (RPE) signals refine behavior by selectively reinforcing neural pathways, revealing a key mechanism through which dopamine guides personalized learning strategies beyond classical reward-based models.<sup>1</sup></p>","PeriodicalId":21766,"journal":{"name":"Signal Transduction and Targeted Therapy","volume":"30 1","pages":""},"PeriodicalIF":52.7000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Signal Transduction and Targeted Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41392-025-02406-5","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

In a recent publication in Cell, Liebana and colleagues demonstrate that dopamine acts as a circuit-specific teaching signal, shaping individual learning trajectories over time. These reward prediction error (RPE) signals refine behavior by selectively reinforcing neural pathways, revealing a key mechanism through which dopamine guides personalized learning strategies beyond classical reward-based models.1

Abstract Image

多巴胺作为一种教学信号:理解它在塑造个体行为中的作用
在最近发表在《细胞》杂志上的一篇文章中,Liebana和他的同事们证明了多巴胺作为一种电路特定的教学信号,随着时间的推移塑造了个体的学习轨迹。这些奖励预测误差(RPE)信号通过选择性地强化神经通路来改善行为,揭示了多巴胺引导个性化学习策略超越经典奖励模型的关键机制
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy Biochemistry, Genetics and Molecular Biology-Genetics
CiteScore
44.50
自引率
1.50%
发文量
384
审稿时长
5 weeks
期刊介绍: Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy. Scope: The journal covers research on major human diseases, including, but not limited to: Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信