{"title":"Managing Severe Type B Aortic Dissection Complications","authors":"Kouomegne Simo MD, MHS, Salim Aziz MD","doi":"10.1016/j.jnma.2025.08.036","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Recurrent aortic dissection (AD) presents significant challenges in both medical and surgical management due to its high risk of severe complications and mortality. Type B AD, in particular, requires careful hemodynamic control and procedural interventions to prevent life-threatening sequelae. This case highlights the complexity of managing a patient with severe Type B AD, recurrent dissections, and multiple post-procedural complications.</div></div><div><h3>Methods</h3><div>A 49-year-old woman with uncontrolled hypertension, hyperlipidemia, and atrial fibrillation presented with sudden onset of chest pain radiating to the back and shoulders. Computed tomography angiography (CTA) revealed Stanford Type B AD with an intramural hematoma extending from the descending thoracic aorta to the aortic bifurcation. Initial management included thoracic endovascular aortic repair (TEVAR). However, she subsequently developed severe complications, including an aorto-esophageal fistula, mediastinitis, new pseudoaneurysms, and a second AD distal to the previous repair. A multidisciplinary approach was employed to manage her condition, incorporating anti-impulse therapy, multiple endovascular and open surgical interventions, and critical care support.</div></div><div><h3>Results</h3><div>Despite extensive medical and surgical efforts—including staged open repair, visceral debranching, and extracorporeal membrane oxygenation (ECMO) initiation—the patient experienced progressive deterioration. Persistent false lumen perfusion, refractory hemodynamic instability, and multi-organ failure ultimately led to cardiac arrest and death.</div></div><div><h3>Conclusion</h3><div>This case underscores the high-risk nature of recurrent Type B AD and the limitations of current treatment strategies. The need for multiple procedures highlights the challenges in achieving long-term stability. A multidisciplinary approach is essential, but further research into optimal management strategies and novel therapeutic options is needed to improve outcomes in such complex cases.</div></div>","PeriodicalId":17369,"journal":{"name":"Journal of the National Medical Association","volume":"117 1","pages":"Pages 17-18"},"PeriodicalIF":2.3000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the National Medical Association","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0027968425002329","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Recurrent aortic dissection (AD) presents significant challenges in both medical and surgical management due to its high risk of severe complications and mortality. Type B AD, in particular, requires careful hemodynamic control and procedural interventions to prevent life-threatening sequelae. This case highlights the complexity of managing a patient with severe Type B AD, recurrent dissections, and multiple post-procedural complications.
Methods
A 49-year-old woman with uncontrolled hypertension, hyperlipidemia, and atrial fibrillation presented with sudden onset of chest pain radiating to the back and shoulders. Computed tomography angiography (CTA) revealed Stanford Type B AD with an intramural hematoma extending from the descending thoracic aorta to the aortic bifurcation. Initial management included thoracic endovascular aortic repair (TEVAR). However, she subsequently developed severe complications, including an aorto-esophageal fistula, mediastinitis, new pseudoaneurysms, and a second AD distal to the previous repair. A multidisciplinary approach was employed to manage her condition, incorporating anti-impulse therapy, multiple endovascular and open surgical interventions, and critical care support.
Results
Despite extensive medical and surgical efforts—including staged open repair, visceral debranching, and extracorporeal membrane oxygenation (ECMO) initiation—the patient experienced progressive deterioration. Persistent false lumen perfusion, refractory hemodynamic instability, and multi-organ failure ultimately led to cardiac arrest and death.
Conclusion
This case underscores the high-risk nature of recurrent Type B AD and the limitations of current treatment strategies. The need for multiple procedures highlights the challenges in achieving long-term stability. A multidisciplinary approach is essential, but further research into optimal management strategies and novel therapeutic options is needed to improve outcomes in such complex cases.
期刊介绍:
Journal of the National Medical Association, the official journal of the National Medical Association, is a peer-reviewed publication whose purpose is to address medical care disparities of persons of African descent.
The Journal of the National Medical Association is focused on specialized clinical research activities related to the health problems of African Americans and other minority groups. Special emphasis is placed on the application of medical science to improve the healthcare of underserved populations both in the United States and abroad. The Journal has the following objectives: (1) to expand the base of original peer-reviewed literature and the quality of that research on the topic of minority health; (2) to provide greater dissemination of this research; (3) to offer appropriate and timely recognition of the significant contributions of physicians who serve these populations; and (4) to promote engagement by member and non-member physicians in the overall goals and objectives of the National Medical Association.