Factors Influencing Hearing Preservation in Cochlear Implant Patients: A Predictive Modelling Approach.

Annette Günther, Oliver J Bott, Andreas Büchner
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Abstract

Introduction: Hearing loss, affecting over 19% of the global population, is a major disability worldwide, with its prevalence expected to increase due to demographic changes. Cochlear implants (CIs) provide a crucial treatment for severe to profound sensorineural hearing loss when conventional hearing aids fail. Although technological and surgical advancements have expanded CI indications, hearing preservation (HP) after implantation remains unpredictable and varies significantly among patients. Recent studies indicate that machine learning (ML) methods could offer improved prediction. Therefore, this study aimed to evaluate the feasibility of predicting HP in potential CI users.

Methods: Clinical data from 225 CI patients (mean age: 59.9 years) implanted at Hannover Medical School (MHH) between 2009 and 2024 were retrospectively analyzed. ML models were developed and compared with baseline models such as linear regression and a mean predictor.

Results: Among all models, the Random Forest (RF) achieved the best predictive performance. Electrode insertion angle and age at implantation were identified as the most influential features for predicting HP, contributing 61.0% and 24.3% respectively. Despite the results of the RF model, limitations such as prediction error and a small dataset were acknowledged.

Conclusion: The study highlights the potential of ML methods for predicting HP in CI users but underscores the need for the integration of more surgical and objective data.

影响人工耳蜗患者听力保存的因素:一种预测模型方法。
听力损失影响着全球19%以上的人口,是世界范围内的一种主要残疾,由于人口结构的变化,其患病率预计会增加。当传统助听器失效时,人工耳蜗为重度到重度感音神经性听力损失提供了重要的治疗方法。尽管技术和手术的进步扩大了人工耳蜗的适应症,但人工耳蜗植入术后的听力保护(HP)仍然是不可预测的,并且在患者之间差异很大。最近的研究表明,机器学习(ML)方法可以提供改进的预测。因此,本研究旨在评估预测潜在CI用户HP的可行性。方法:回顾性分析2009年至2024年汉诺威医学院(MHH) 225例CI植入患者的临床资料,平均年龄59.9岁。开发ML模型并与基线模型(如线性回归和平均预测器)进行比较。结果:在所有模型中,随机森林(Random Forest, RF)的预测性能最好。电极插入角度和植入年龄是预测HP最重要的特征,分别占61.0%和24.3%。尽管射频模型的结果,局限性,如预测误差和一个小的数据集被承认。结论:该研究强调了ML方法预测CI使用者HP的潜力,但强调了整合更多手术和客观数据的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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