Association between dietary creatine intake and serum biomarkers of spermatogenesis in males aged 12 years and older.

IF 3.4 Q2 REPRODUCTIVE BIOLOGY

Reproduction & fertility Pub Date : 2025-09-03 Print Date: 2025-07-01 DOI:10.1530/RAF-25-0009

David Nedeljkovic, Nikola Todorovic, Tonje Holte Stea, Dagrun Engeset, Sergej M Ostojic

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Abstract

Graphical abstract:

Lay summary: Creatine is a nutrient that helps provide energy to different parts of the body, including the testes. Since making sperm takes a lot of energy, creatine might play a role in supporting sperm health. Some studies suggest it could help, while others raise concerns. However, it is still unclear what effect, if any, creatine from food has on sperm. To learn more, we looked at data from over 1,300 males in the US, aged 12 and older. We compared how much creatine they got from their diet with levels of two hormones in the blood that are related to sperm production. We found no strong link between dietary creatine and these hormone levels. This suggests that creatine from food probably does not have a major effect - good or bad - on male reproductive health. Since this study used existing data and did not test creatine directly in an experiment, we cannot say for sure if creatine causes any changes. More research, especially studies that look directly at sperm, is needed to better understand how creatine might affect fertility.

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膳食肌酸摄入量与12岁及以上男性精子发生血清生物标志物之间的关系

图解摘要：概要：肌酸是一种营养物质，有助于为身体的不同部位提供能量，包括睾丸。由于制造精子需要大量的能量，肌酸可能在支持精子健康方面发挥作用。一些研究表明它可能有所帮助，而另一些研究则提出了担忧。然而，目前还不清楚食物中的肌酸对精子有什么影响，如果有的话。为了了解更多，我们研究了1300多名12岁及以上的美国男性的数据。我们比较了他们从饮食中获得的肌酸与血液中与精子产生有关的两种激素的水平。我们发现饮食中的肌酸和这些激素水平之间没有很强的联系。这表明，食物中的肌酸可能对男性生殖健康没有重大影响——无论是好是坏。由于这项研究使用了现有的数据，并没有在实验中直接测试肌酸，我们不能肯定地说肌酸是否会引起任何变化。需要更多的研究，特别是直接观察精子的研究，来更好地了解肌酸如何影响生育能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reproduction & fertility

CiteScore

2.80

自引率

0.00%

发文量