{"title":"Psychosocial Phenotype and Risky Sexual Behavior Among People Living with HIV in Changsha: A Latent Profile Analysis.","authors":"Qiaoyue Lu, Yixuan Li, Ziqi Qin, Yuqiong Duan, Honghong Wang, Xueling Xiao","doi":"10.1080/19317611.2025.2509113","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to explore the psychosocial phenotype and its association with risky sexual behavior to deepen the understanding of the mechanisms of risky sexual behavior (RSB) among people living with HIV.</p><p><strong>Methods: </strong>Data were collected between October and December 2021 in a cross-sectional study. Participants were 727 people living with HIV from an HIV clinic in a comprehensive hospital and completed a battery of questionnaires. A latent profile approach was utilized to identify the psychosocial phenotype based on depression, stigma, and social support. Multinomial logistic regression was used to investigate the relationship between sexual behaviors and the psychosocial phenotype.</p><p><strong>Results: </strong>Three distinct phenotypes were identified: a low-risk profile (52.68%), a middle-risk profile (37.96%), and a high-risk profile (9.35%). These profiles exhibited a gradually increasing level of depression and stigma but a decreased level of social support. Participants in the middle-risk profile were twice as likely to engage in risky sexual behavior than those in low-risk profile (OR = 1.924, <i>p</i> = .008).</p><p><strong>Conclusions: </strong>This study implies the synergistic impact of depression, stigma, and social support on the occurrence of risky sexual behavior among people living with HIV, which may be useful to the early intervention of risky sexual behavior.</p>","PeriodicalId":46855,"journal":{"name":"International Journal of Sexual Health","volume":"37 3","pages":"457-467"},"PeriodicalIF":2.1000,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366811/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Sexual Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/19317611.2025.2509113","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: This study aimed to explore the psychosocial phenotype and its association with risky sexual behavior to deepen the understanding of the mechanisms of risky sexual behavior (RSB) among people living with HIV.
Methods: Data were collected between October and December 2021 in a cross-sectional study. Participants were 727 people living with HIV from an HIV clinic in a comprehensive hospital and completed a battery of questionnaires. A latent profile approach was utilized to identify the psychosocial phenotype based on depression, stigma, and social support. Multinomial logistic regression was used to investigate the relationship between sexual behaviors and the psychosocial phenotype.
Results: Three distinct phenotypes were identified: a low-risk profile (52.68%), a middle-risk profile (37.96%), and a high-risk profile (9.35%). These profiles exhibited a gradually increasing level of depression and stigma but a decreased level of social support. Participants in the middle-risk profile were twice as likely to engage in risky sexual behavior than those in low-risk profile (OR = 1.924, p = .008).
Conclusions: This study implies the synergistic impact of depression, stigma, and social support on the occurrence of risky sexual behavior among people living with HIV, which may be useful to the early intervention of risky sexual behavior.
期刊介绍:
As the official journal of the World Association for Sexual Health, the International Journal of Sexual Health promotes sexual health as a state of physical, emotional, mental, and social well-being through a positive approach to sexuality and sexual rights. The journal publishes peer-reviewed scientific papers, editorials, and reviews, using quantitative and qualitative methods, descriptive and critical analysis, instrument development, surveys, and case studies to examine the essential elements of this broad concept. Leading experts from around the world present original work that covers a variety of disciplines, including sexology, biology, medicine, psychology, sociology, anthropology, history, and religion.