The Relationship of Age of First Sexual Activity to Pain and Psychological Symptoms Among Women with Urogenital Pain.

IF 3 3区 医学 Q1 ANESTHESIOLOGY
Pain Medicine Pub Date : 2025-08-25 DOI:10.1093/pm/pnaf117
Britney Abro, Marjorie Heule, Laura Krasean, Janice Tomakowsky, Bernadette Zwaans, Mark A Lumley
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Abstract

Objective: Age of first sexual activity (AFSA) may be a developmental marker linked to later clinical status (e.g., pain, depression). However, correlates of AFSA have not been examined in chronic pain populations and are unknown in women with urogenital pain.

Methods: A series of 309 women (age M = 48.4 years) presenting to a tertiary women's urology center with urogenital pain completed a comprehensive intake survey, which included their AFSA and measures of pain severity and interference, depression, anxiety, adverse childhood experiences, and childhood abuse.

Results: The mean AFSA was 18 years (median = 17). AFSA was significantly, inversely related to pain intensity (r = -0.16), pain interference (r = -0.20), and depression (r = -0.11). Curvilinear (quadratic) associations were also identified; scatter plots and age-group comparisons showed that these inverse relationships flattened or slightly reversed for AFSA after the college years. Analyses also found that childhood adversities and childhood abuse predicted an earlier AFSA.

Conclusions: Among women with urogenital pain, an earlier AFSA is associated with worse pain and distress, at least through the college years. Earlier sexual activity may directly increase risk for later pain and distress or serve as a marker of other risk factors-such as childhood adversity or abuse. A relatively late AFSA is not protective in this sample, perhaps due to psychological or interpersonal factors associated with a later first sexual experience. Clinical inquiry into AFSA may provide insight into risk factors for urogenital pain and distress.

第一次性行为年龄与女性泌尿生殖系统疼痛及心理症状的关系
目的:第一次性行为年龄(AFSA)可能是一个与后期临床状态(如疼痛、抑郁)相关的发育标志。然而,AFSA的相关性尚未在慢性疼痛人群中进行检查,并且在患有泌尿生殖系统疼痛的女性中尚不清楚。方法:309名女性(年龄48.4岁)因泌尿系统疼痛就诊于一家三级女性泌尿外科中心,完成了一项全面的摄入调查,包括她们的AFSA、疼痛严重程度和干扰、抑郁、焦虑、童年不良经历和童年虐待的测量。结果:AFSA的平均年龄为18岁(中位为17岁)。AFSA与疼痛强度(r = -0.16)、疼痛干扰(r = -0.20)和抑郁(r = -0.11)呈显著负相关。曲线(二次)关联也被确定;散点图和年龄组比较显示,在大学毕业后,这些反向关系趋于平缓或略有逆转。分析还发现,童年逆境和童年虐待预示着更早的AFSA。结论:在患有泌尿生殖系统疼痛的女性中,早期的AFSA与更严重的疼痛和痛苦有关,至少在大学期间是这样。过早的性行为可能会直接增加日后疼痛和痛苦的风险,或者作为其他风险因素的标志——比如童年的逆境或虐待。相对较晚的AFSA在这个样本中没有保护作用,可能是由于心理或人际因素与较晚的第一次性经历有关。对AFSA的临床调查可能有助于了解泌尿生殖系统疼痛和痛苦的危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pain Medicine
Pain Medicine 医学-医学:内科
CiteScore
6.50
自引率
3.20%
发文量
187
审稿时长
3 months
期刊介绍: Pain Medicine is a multi-disciplinary journal dedicated to pain clinicians, educators and researchers with an interest in pain from various medical specialties such as pain medicine, anaesthesiology, family practice, internal medicine, neurology, neurological surgery, orthopaedic spine surgery, psychiatry, and rehabilitation medicine as well as related health disciplines such as psychology, neuroscience, nursing, nurse practitioner, physical therapy, and integrative health.
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