Three-Dimensional Magnetic Resonance Imaging of Median Nerve Volume for Assessing Carpal Tunnel Syndrome Severity.

IF 3.1 3区医学 Q2 CLINICAL NEUROLOGY

Muscle & Nerve Pub Date : 2025-11-01 Epub Date: 2025-08-28 DOI:10.1002/mus.70010

Kazuki Hayakawa, Taku Suzuki, Katsuhiko Hayakawa, Yusuke Kawano, Takuji Iwamoto, Nobuyuki Fujita

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引用次数: 0

Abstract

Introduction/aims: 3D magnetic resonance imaging (MRI) is a tool for visualizing and quantifying the volume of the median nerve; however, the diagnostic value of the volume of the median nerve for assessing CTS severity is unclear. This study aimed to evaluate the utility of 3T MRI combined with three-dimensional (3D) imaging to assess the cross-sectional volume (CSV) of the median nerve for diagnosing carpal tunnel syndrome (CTS) and determining its severity.

Methods: We used MRI to measure the CSV of the median nerve in 95 patients with CTS and 26 healthy controls. CTS severity was graded according to the Padua classification, and differences in CSV according to severity were analyzed.

Results: The mean CSVs for the severity groups were as follows: control, 22.4 mm³; minimal, 28.8 mm³; moderate, 34.4 mm³; severe, 53.6 mm³; and extreme, 48.3 mm³. CSV increased with CTS severity, with significantly higher values in the severe and extreme groups compared with the moderate, minimal, and control groups.

Discussion: This study showed that the CSV of the median nerve increased with disease severity, both visually and in three dimensions. This helps to visually understand the severity of CTS, and the association between morphology and disease severity may contribute to a better understanding of the pathophysiology of CTS.

Abstract Image

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正中神经体积三维磁共振成像评估腕管综合征严重程度。

简介/目的：三维磁共振成像（MRI）是一种可视化和量化正中神经体积的工具；然而，正中神经体积对评估CTS严重程度的诊断价值尚不清楚。本研究旨在评估3T MRI结合三维（3D）成像评估正中神经横截体积（CSV）在诊断腕管综合征（CTS）和确定其严重程度中的应用价值。方法：采用MRI对95例CTS患者和26例健康对照进行正中神经CSV测量。根据Padua分级对CTS严重程度进行分级，分析不同严重程度的CSV差异。结果：严重组的平均csv值为：对照组22.4 mm3；最小，28.8 mm3；中等，34.4 mm3；重度，53.6 mm3；极端的48.3毫米。CSV随CTS严重程度的增加而增加，与中度、轻度和对照组相比，严重和极端组的CSV值显著高于中度、轻度和对照组。讨论：本研究显示，正中神经的CSV随疾病严重程度而增加，无论是视觉上还是三维上。这有助于直观地了解CTS的严重程度，并且形态学与疾病严重程度之间的关联可能有助于更好地了解CTS的病理生理学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Muscle & Nerve 医学-临床神经学

CiteScore

6.40

自引率

5.90%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Muscle & Nerve is an international and interdisciplinary publication of original contributions, in both health and disease, concerning studies of the muscle, the neuromuscular junction, the peripheral motor, sensory and autonomic neurons, and the central nervous system where the behavior of the peripheral nervous system is clarified. Appearing monthly, Muscle & Nerve publishes clinical studies and clinically relevant research reports in the fields of anatomy, biochemistry, cell biology, electrophysiology and electrodiagnosis, epidemiology, genetics, immunology, pathology, pharmacology, physiology, toxicology, and virology. The Journal welcomes articles and reports on basic clinical electrophysiology and electrodiagnosis. We expedite some papers dealing with timely topics to keep up with the fast-moving pace of science, based on the referees'' recommendation.