Zhengfu Chen, Lifu Hu, Zixian Guo, Jingxiang Chu, Tao He, Changyong E, Tao Jiang
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引用次数: 0
Abstract
Introduction: Intrahepatic biliary neuroendocrine neoplasms (NENs) are rare neoplasms originating from neuroendocrine cells in the intrahepatic bile ducts. Patients often present without hormone-related symptoms but are admitted due to jaundice or abdominal pain.
Presentation of case: This case report describes a 57-year-old female patient who experienced intermittent upper abdominal pain for one month prior to admission. A computed tomography (CT) scan at a local hospital revealed an intrahepatic space-occupying lesion. Magnetic Resonance Cholangiopancreatography (MRCP) at our hospital identified a mass at the root of the left hepatic duct, accompanied by secondary dilation of the left intrahepatic bile ducts. Liver function tests and tumor markers were within normal ranges, and no jaundice or metastatic signs were observed. The patient underwent robot-assisted left hemihepatectomy and cholecystectomy, with a smooth postoperative recovery. Pathological examination confirmed a neuroendocrine tumor (NET G2), measuring 2.2×2×1.6 cm. Postoperative positron emission tomography / computedtomography (PET/CT) scans detected no tumors elsewhere, confirming the intrahepatic bile duct as the primary site.
Conclusion: Biliary NENs are exceedingly rare and challenging to diagnose preoperatively. Surgical resection remains the most effective treatment for achieving cure or prolonging survival.
期刊介绍：
The Journal of Gastrointestinal Cancer is a multidisciplinary medium for the publication of novel research pertaining to cancers arising from the gastrointestinal tract.The journal is dedicated to the most rapid publication possible.The journal publishes papers in all relevant fields, emphasizing those studies that are helpful in understanding and treating cancers affecting the esophagus, stomach, liver, gallbladder and biliary tree, pancreas, small bowel, large bowel, rectum, and anus. In addition, the Journal of Gastrointestinal Cancer publishes basic and translational scientific information from studies providing insight into the etiology and progression of cancers affecting these organs. New insights are provided from diverse areas of research such as studies exploring pre-neoplastic states, risk factors, epidemiology, genetics, preclinical therapeutics, surgery, radiation therapy, novel medical therapeutics, clinical trials, and outcome studies.In addition to reports of original clinical and experimental studies, the journal also publishes: case reports, state-of-the-art reviews on topics of immediate interest or importance; invited articles analyzing particular areas of pancreatic research and knowledge; perspectives in which critical evaluation and conflicting opinions about current topics may be expressed; meeting highlights that summarize important points presented at recent meetings; abstracts of symposia and conferences; book reviews; hypotheses; Letters to the Editors; and other items of special interest, including:Complex Cases in GI Oncology: This is a new initiative to provide a forum to review and discuss the history and management of complex and involved gastrointestinal oncology cases. The format will be similar to a teaching case conference where a case vignette is presented and is followed by a series of questions and discussion points. A brief reference list supporting the points made in discussion would be expected.
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