Pleomorphic carcinoma of the lung with paraneoplastic fever as presentation.

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian Journal of Thoracic and Cardiovascular Surgery Pub Date : 2025-09-01 Epub Date: 2025-05-31 DOI:10.1007/s12055-025-01976-x

Naveen Kumar Kushwaha, Laleng Mawia Darlong, Sunil Pasricha

引用次数: 0

Abstract

Pulmonary pleomorphic carcinoma (PPC) is a rare, highly aggressive variant of non-small cell lung cancer (NSCLC), comprising 0.1-0.4% of all pulmonary malignancies. While lung cancers typically present with symptoms like cough and hemoptysis, paraneoplastic syndromes are observed in about 10% of cases. Paraneoplastic fever as an initial manifestation is extremely rare. We present a rare case of PPC with neoplastic fever, emphasizing the importance of paraneoplastic syndromes during the evaluation of lung cancer. Surgical resection successfully alleviates neoplastic fever, highlighting the need to recognize paraneoplastic fever as a diagnostic challenge and consider it as a differential in cases of unexplained fever for prompt intervention.

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以副肿瘤性发热为表现的多形性肺癌。

肺多形性癌（PPC）是一种罕见的、高度侵袭性的非小细胞肺癌（NSCLC）变体，占所有肺部恶性肿瘤的0.1-0.4%。虽然肺癌通常表现为咳嗽和咯血等症状，但在约10%的病例中观察到副肿瘤综合征。副肿瘤热作为初始表现是极其罕见的。我们报告一个罕见的PPC伴肿瘤热的病例，强调在评估肺癌时副肿瘤综合征的重要性。手术切除成功地减轻了肿瘤性发热，强调需要认识到副肿瘤性发热是一种诊断挑战，并将其视为原因不明的发热病例的鉴别诊断，以便及时干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.20

自引率

14.30%

发文量

141

期刊介绍： The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.