Intestinal organoids as advanced modeling platform for food research: a review.

IF 8.8 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY
Xu Wang, Yanqiu Xia, Jin Wang, Yan Zhang, Pin Lv, Yi Wang
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引用次数: 0

Abstract

Intestinal organoids have emerged as powerful tools in biomedical research, offering a physiologically relevant model of the gut that can replicate the functions and microenvironments of the human intestine. In this study, we conducted a scientific review of the development and commonly used detection methods for intestinal organoids. Drawing from existing studies, we summarized the applications of intestinal organoids in food research. Intestinal organoids have revolutionized the field of food research by providing a sophisticated and physiologically relevant model system to study the complex interactions between food components, the gut microbiota and food safety. Based on these limitations, we propose that integration of intelligent strategies such as engineering and artificial intelligence technology with intestinal organoids will become a powerful tool for food innovation and personalized nutrition in the future.

肠道类器官作为食品研究的先进建模平台综述
肠道类器官已成为生物医学研究的有力工具,提供了一种与肠道生理学相关的模型,可以复制人类肠道的功能和微环境。在本研究中,我们对肠道类器官的发展和常用检测方法进行了科学综述。结合已有研究,综述了肠道类器官在食品研究中的应用。肠道类器官为研究食品成分、肠道微生物群和食品安全之间复杂的相互作用提供了一个复杂的生理相关模型系统,从而彻底改变了食品研究领域。基于这些局限性,我们提出将工程和人工智能技术等智能策略与肠道类器官相结合将成为未来食品创新和个性化营养的有力工具。
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来源期刊
CiteScore
22.60
自引率
4.90%
发文量
600
审稿时长
7.5 months
期刊介绍: Critical Reviews in Food Science and Nutrition serves as an authoritative outlet for critical perspectives on contemporary technology, food science, and human nutrition. With a specific focus on issues of national significance, particularly for food scientists, nutritionists, and health professionals, the journal delves into nutrition, functional foods, food safety, and food science and technology. Research areas span diverse topics such as diet and disease, antioxidants, allergenicity, microbiological concerns, flavor chemistry, nutrient roles and bioavailability, pesticides, toxic chemicals and regulation, risk assessment, food safety, and emerging food products, ingredients, and technologies.
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