Cutoff points for sedentary behavior and their capacity to predict mortality in individuals with COPD: A 12- year follow-up study.

IF 2.3 3区医学 Q2 RESPIRATORY SYSTEM

Chronic Respiratory Disease Pub Date : 2025-01-01 Epub Date: 2025-08-23 DOI:10.1177/14799731251366956

Lais Santin, Humberto Silva, Thais Moçatto Tofoli, Letícia Medeiros, Karina Couto Furlanetto, Fabio Pitta

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Abstract

ObjectiveThis study aimed to identify the usefulness and compare three cutoff points of sedentary behavior (i.e., >8.5 h/day in sedentary time [ST], >70% of the awake time spent in ST, and <4300 steps/day) as predictors of all-cause mortality over a 12-years follow-up period in individuals with stable COPD.MethodsBaseline-only data from 92 individuals with COPD assessed for admission to pulmonary rehabilitation were analyzed.ResultsCox multivariate regression models identified the cutoff point of ST >8.5 h/day as an independent predictor of mortality after adjusting for confounders (hazard ratio 1.23, 95% CI 1.021 - 1.589, P = 0.02). The other two cutoffs were not significant.ConclusionAmong different cutoffs indicating sedentary behavior, ST >8.5 h/day was identified as an independent indicator of higher mortality risk in a 12-years follow-up period in individuals with stable COPD, indicating a 23% higher mortality risk in comparison to those who present ST <8.5 h/day.

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久坐行为的截止点及其预测COPD患者死亡率的能力：一项为期12年的随访研究。

本研究旨在确定并比较久坐行为的三个截止点（即，久坐时间[ST]中每天8.5小时，ST中70%清醒时间，8.5小时/天）在调整混杂因素后作为死亡率的独立预测因子的有效性（风险比1.23,95% CI 1.021 - 1.589, P = 0.02）。另外两个临界值并不显著。结论：在表明久坐行为的不同截止点中，在12年随访期间，稳定型COPD患者的ST >8.5 h/天被确定为死亡风险较高的独立指标，与存在ST的患者相比，ST >8.5 h/天的死亡率风险高23%

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来源期刊

Chronic Respiratory Disease RESPIRATORY SYSTEM-

CiteScore

5.90

自引率

7.30%

发文量

审稿时长

11 weeks

期刊介绍： Chronic Respiratory Disease is a peer-reviewed, open access, scholarly journal, created in response to the rising incidence of chronic respiratory diseases worldwide. It publishes high quality research papers and original articles that have immediate relevance to clinical practice and its multi-disciplinary perspective reflects the nature of modern treatment. The journal provides a high quality, multi-disciplinary focus for the publication of original papers, reviews and commentary in the broad area of chronic respiratory disease, particularly its treatment and management.