B. Nancharaiah, Lakshmi Sevukamoorthy, Bhavya G, T. M. Sathish Kumar, T. R. Vijaya Lakshmi, Swapna Siddamsetti
{"title":"A Smart Intelligent Internet of Things Framework for Predicting Mental Health","authors":"B. Nancharaiah, Lakshmi Sevukamoorthy, Bhavya G, T. M. Sathish Kumar, T. R. Vijaya Lakshmi, Swapna Siddamsetti","doi":"10.1002/adts.202500048","DOIUrl":null,"url":null,"abstract":"Crohn's disease is a chronic inflammatory condition affecting the gastrointestinal tract, and it presents significant challenges in both diagnosis and management due to its complex and multifactorial causes. Early identification of Crohn's disease is crucial, as it can lead to timely interventions, improve patient outcomes, and reduce healthcare costs. This study aims to develop predictive models using advanced analytics, machine learning (ML), and clinical data to identify individuals at risk for Crohn's disease.The proposed framework integrates a variety of data sources, including genetic predispositions, microbiome profiles, environmental factors, and clinical markers such as inflammatory biomarkers, endoscopic findings, and patient‐reported symptoms. We employed supervised ML algorithms, including random forests, support vector machines (SVM), and deep learning models, to analyze retrospective datasets from multiple cohorts.The results indicate that these predictive models can achieve high sensitivity and specificity in identifying early‐onset Crohn's disease. Key predictors identified include specific genetic mutations (e.g., NOD2/CARD15), imbalances in gut microbiota, and elevated levels of C‐reactive protein (CRP).A pair of knee x‐ray pictures obtained from the Kaggle website are utilised to assess the proposed ZMPPM. Finally, the performance is evaluated based on metrics like accuracy, F1‐score, recall, precision, specificity and error rate. The model attained an excellent accuracy of 99% with relatively minor error.","PeriodicalId":7219,"journal":{"name":"Advanced Theory and Simulations","volume":"32 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Theory and Simulations","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/adts.202500048","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Crohn's disease is a chronic inflammatory condition affecting the gastrointestinal tract, and it presents significant challenges in both diagnosis and management due to its complex and multifactorial causes. Early identification of Crohn's disease is crucial, as it can lead to timely interventions, improve patient outcomes, and reduce healthcare costs. This study aims to develop predictive models using advanced analytics, machine learning (ML), and clinical data to identify individuals at risk for Crohn's disease.The proposed framework integrates a variety of data sources, including genetic predispositions, microbiome profiles, environmental factors, and clinical markers such as inflammatory biomarkers, endoscopic findings, and patient‐reported symptoms. We employed supervised ML algorithms, including random forests, support vector machines (SVM), and deep learning models, to analyze retrospective datasets from multiple cohorts.The results indicate that these predictive models can achieve high sensitivity and specificity in identifying early‐onset Crohn's disease. Key predictors identified include specific genetic mutations (e.g., NOD2/CARD15), imbalances in gut microbiota, and elevated levels of C‐reactive protein (CRP).A pair of knee x‐ray pictures obtained from the Kaggle website are utilised to assess the proposed ZMPPM. Finally, the performance is evaluated based on metrics like accuracy, F1‐score, recall, precision, specificity and error rate. The model attained an excellent accuracy of 99% with relatively minor error.
期刊介绍:
Advanced Theory and Simulations is an interdisciplinary, international, English-language journal that publishes high-quality scientific results focusing on the development and application of theoretical methods, modeling and simulation approaches in all natural science and medicine areas, including:
materials, chemistry, condensed matter physics
engineering, energy
life science, biology, medicine
atmospheric/environmental science, climate science
planetary science, astronomy, cosmology
method development, numerical methods, statistics