Dual Diversity and Pseudo-Label Correction Learning for Semi-Supervised Medical Image Segmentation

IF 2.5 4区 计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC
Guangxing Du, Rui Wu, Jinming Xu, Xiang Zeng, Shengwu Xiong
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引用次数: 0

Abstract

Semi-supervised medical image segmentation has recently gained increasing research attention as it can reduce the need for large-scale annotated data. Current mainstream methods usually adopt two sub-networks and encourage the two models to make consistent predictions for the same segmentation task through consistency regularization. However, the scarcity of medical samples reduces the effectiveness of consistency constraints, and this problem may be further exacerbated by the influence of noisy pseudo-labels. In this work, we propose a novel co-training framework based on dual diversity and pseudo-label correction learning (DDPCL) to address these challenges. Specifically, firstly, we design a dual diversity learning strategy, in which data diversity fully mines the potential information of limited training samples through the CutMix operation, and feature diversity promotes the model to learn complementary feature representations by minimizing the similarity between the features extracted by the two sub-networks. Secondly, we propose a pseudo-label correction learning strategy, which regards the inconsistent region where the pseudo-labels predicted by the two sub-networks are different as potential bias regions, and guides the models to correct the bias in these regions. Extensive experiments on three public datasets (ACDC, LA and Pancreas-NIH datasets) validate that the proposed method outperforms the state-of-the-art semi-supervised medical image segmentation. The code is available at http://github.com/ddd0420/ddpcl.

半监督医学图像分割的双多样性和伪标签校正学习
半监督医学图像分割由于可以减少对大规模标注数据的需求,近年来得到了越来越多的研究关注。目前的主流方法通常采用两个子网络,通过一致性正则化鼓励两个模型对同一分割任务做出一致的预测。然而,医学样本的稀缺性降低了一致性约束的有效性,并且这一问题可能会因带有噪声的伪标签的影响而进一步加剧。在这项工作中,我们提出了一种基于双重多样性和伪标签校正学习(DDPCL)的新型协同训练框架来解决这些挑战。具体而言,首先,我们设计了双多样性学习策略,其中数据多样性通过CutMix操作充分挖掘有限训练样本的潜在信息,特征多样性通过最小化两个子网络提取的特征之间的相似性来促进模型学习互补特征表示。其次,我们提出了一种伪标签校正学习策略,该策略将两个子网络预测的伪标签不一致的区域作为潜在的偏差区域,并引导模型对这些区域中的偏差进行校正。在三个公共数据集(ACDC, LA和pancreatic - nih数据集)上进行的大量实验验证了所提出的方法优于最先进的半监督医学图像分割。代码可在http://github.com/ddd0420/ddpcl上获得。
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来源期刊
International Journal of Imaging Systems and Technology
International Journal of Imaging Systems and Technology 工程技术-成像科学与照相技术
CiteScore
6.90
自引率
6.10%
发文量
138
审稿时长
3 months
期刊介绍: The International Journal of Imaging Systems and Technology (IMA) is a forum for the exchange of ideas and results relevant to imaging systems, including imaging physics and informatics. The journal covers all imaging modalities in humans and animals. IMA accepts technically sound and scientifically rigorous research in the interdisciplinary field of imaging, including relevant algorithmic research and hardware and software development, and their applications relevant to medical research. The journal provides a platform to publish original research in structural and functional imaging. The journal is also open to imaging studies of the human body and on animals that describe novel diagnostic imaging and analyses methods. Technical, theoretical, and clinical research in both normal and clinical populations is encouraged. Submissions describing methods, software, databases, replication studies as well as negative results are also considered. The scope of the journal includes, but is not limited to, the following in the context of biomedical research: Imaging and neuro-imaging modalities: structural MRI, functional MRI, PET, SPECT, CT, ultrasound, EEG, MEG, NIRS etc.; Neuromodulation and brain stimulation techniques such as TMS and tDCS; Software and hardware for imaging, especially related to human and animal health; Image segmentation in normal and clinical populations; Pattern analysis and classification using machine learning techniques; Computational modeling and analysis; Brain connectivity and connectomics; Systems-level characterization of brain function; Neural networks and neurorobotics; Computer vision, based on human/animal physiology; Brain-computer interface (BCI) technology; Big data, databasing and data mining.
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