Longitudinal Study on Psychological Distress Trajectory and Influencing Factors of Kidney Transplant Patients: A Potential Category Analysis Study

IF 1.9 4区 医学 Q2 SURGERY
Xiaoting Zheng, Xingwang Yao
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引用次数: 0

Abstract

Introduction

Although kidney transplantation confers substantial benefits, patients also exhibit varying levels of psychological distress attributable to multiple factors, with significant heterogeneity observed in their trajectories of change.

Objectives

This study investigates latent heterogeneous trajectories of psychological distress in kidney transplant recipients (KTRs) from pre-transplantation to 6 months postoperatively. It tests the core hypothesis that high Neuroticism (N) and Psychoticism (P) scores serve as key distinguishing predictors of these trajectory classes. The analysis also explores the influence of sociodemographic and clinical factors on class membership. By elucidating distress patterns and their underlying drivers, this research aims to facilitate early identification of high-risk patients and inform the development of personalized psychological interventions, ultimately improving treatment adherence and long-term quality of life.

Materials and Methods

A convenience sampling method was used to select 326 kidney transplant patients from the kidney transplant department of a tertiary hospital in Changsha, Hunan Province, from September 2022 to August 2024 as the research subjects. We conducted a cross-sectional survey design by using three standardized instruments: Sociodemographic variables, Eysenck Personality Questionnaire Short Scale-Chinese, and Psychological Distress Thermometer (DT) were collected at four time points: preoperative (T0), postoperative 1 week (T1), 1 month (T2), and 6 months (T3). Using a latent variable growth model to identify the developmental trajectory of psychological distress and explore its influencing factors.

Results

Three heterogeneous psychological distress trajectory classes were identified. Membership in these classes was significantly associated with the clinical course of illness, household income, and personality traits.

Conclusions

Psychological distress in KTRs exhibits significant population heterogeneity. Clinicians can utilize patients' distress trajectory patterns and temperament characteristics to implement personalized care protocols, thereby reducing distress levels.

肾移植患者心理困扰轨迹及影响因素的纵向研究:一项潜在类别分析研究
尽管肾移植带来了巨大的益处,但由于多种因素,患者也表现出不同程度的心理困扰,在其变化轨迹中观察到显著的异质性。目的研究肾移植受者(KTRs)从移植前到术后6个月心理困扰的潜在异质性轨迹。它验证了高神经质(N)和精神病(P)分数作为这些轨迹类别的关键区分预测因子的核心假设。分析还探讨了社会人口学和临床因素对班级成员的影响。通过阐明痛苦模式及其潜在驱动因素,本研究旨在促进高危患者的早期识别,并为个性化心理干预的发展提供信息,最终提高治疗依从性和长期生活质量。材料与方法采用方便抽样方法,选取2022年9月至2024年8月湖南省长沙市某三级医院肾移植科肾移植患者326例作为研究对象。在术前(T0)、术后1周(T1)、1个月(T2)和6个月(T3)四个时间点,采用社会人口学变量、艾森克人格问卷短量表-中文和心理困扰温度计(DT)三种标准化工具进行横断面调查设计。运用潜在变量成长模型识别心理困扰的发展轨迹并探讨其影响因素。结果确定了三种不同的心理困扰轨迹。这些班级的成员与疾病的临床病程、家庭收入和人格特征显著相关。结论ktr患者的心理困扰存在明显的人群异质性。临床医生可以利用患者的痛苦轨迹模式和气质特征来实施个性化的护理方案,从而降低痛苦程度。
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来源期刊
Clinical Transplantation
Clinical Transplantation 医学-外科
CiteScore
3.70
自引率
4.80%
发文量
286
审稿时长
2 months
期刊介绍: Clinical Transplantation: The Journal of Clinical and Translational Research aims to serve as a channel of rapid communication for all those involved in the care of patients who require, or have had, organ or tissue transplants, including: kidney, intestine, liver, pancreas, islets, heart, heart valves, lung, bone marrow, cornea, skin, bone, and cartilage, viable or stored. Published monthly, Clinical Transplantation’s scope is focused on the complete spectrum of present transplant therapies, as well as also those that are experimental or may become possible in future. Topics include: Immunology and immunosuppression; Patient preparation; Social, ethical, and psychological issues; Complications, short- and long-term results; Artificial organs; Donation and preservation of organ and tissue; Translational studies; Advances in tissue typing; Updates on transplant pathology;. Clinical and translational studies are particularly welcome, as well as focused reviews. Full-length papers and short communications are invited. Clinical reviews are encouraged, as well as seminal papers in basic science which might lead to immediate clinical application. Prominence is regularly given to the results of cooperative surveys conducted by the organ and tissue transplant registries. Clinical Transplantation: The Journal of Clinical and Translational Research is essential reading for clinicians and researchers in the diverse field of transplantation: surgeons; clinical immunologists; cryobiologists; hematologists; gastroenterologists; hepatologists; pulmonologists; nephrologists; cardiologists; and endocrinologists. It will also be of interest to sociologists, psychologists, research workers, and to all health professionals whose combined efforts will improve the prognosis of transplant recipients.
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