A comprehensive review of the autoimmune pathogenesis of acquired hemophilia A

IF 3.4 3区医学 Q1 HEMATOLOGY

Thrombosis research Pub Date : 2025-08-26 DOI:10.1016/j.thromres.2025.109444

Jose Pardos-Gea , Jordi Barquinero , Iñaki Alvarez , Vicente Cortina , Iris Garcia Martínez , Laura Martín Fernández , Francisco Vidal

引用次数: 0

Abstract

Acquired haemophilia A (AHA) constitutes the most frequent form of autoimmunity againts coagulation factors. The pathogenic basis of anti-FVIII autoantibodies production remains unknown and our narrative review explores the possible causes and provides an overview of evidence data.

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获得性血友病A自身免疫发病机制综述

获得性血友病A （AHA）是最常见的针对凝血因子的自身免疫。抗fviii自身抗体产生的致病基础尚不清楚，我们的叙述性综述探讨了可能的原因，并提供了证据数据的概述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Thrombosis research 医学-外周血管病

CiteScore

14.60

自引率

4.00%

发文量

364

审稿时长

31 days

期刊介绍： Thrombosis Research is an international journal dedicated to the swift dissemination of new information on thrombosis, hemostasis, and vascular biology, aimed at advancing both science and clinical care. The journal publishes peer-reviewed original research, reviews, editorials, opinions, and critiques, covering both basic and clinical studies. Priority is given to research that promises novel approaches in the diagnosis, therapy, prognosis, and prevention of thrombotic and hemorrhagic diseases.