DuTOC: The prospective Dutch Thoracic Oncology Cohort: A nationwide infrastructure to collect clinical data, PROMS and bio-material to support thoracic oncology studies

IF 4.4 2区医学 Q1 ONCOLOGY

Lung Cancer Pub Date : 2025-08-26 DOI:10.1016/j.lungcan.2025.108728

W.K. de Jong , F.T.A. van der Velde , A. Keijser , H.J.M. Groen , A.S.R. van Lindert , G.R. Vink , L.E.L. Hendriks , M.M. van den Heuvel , on behalf of the DuTOC scientific committee

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引用次数: 0

Abstract

The Dutch Thoracic Oncology Cohort (DuTOC) is a nationwide cohort for patients with thoracic malignancies collecting patient characteristics, quality of life and biomaterials after informed consent of the patient. With this data and material DuTOC is a solid infrastructure for retrospective and prospective studies involving treatment, (molecular) diagnostics, quality control, biomarkers and translational research and quality of life.

DuTOC is initiated by the Dutch Association of Pulmonologists and is a collaboration of all clinicians involved in cancer-care and other stakeholders in the field of thoracic malignancies such as patient advocacies, health regulatory agencies, cancer registries and pharmaceutical companies.

DuTOC has the ambition to automate real-time data acquisition. This minimizes the workload of the research staff and facilitates the transition to a self-learning health care system based on real-time data, incorporating long-term longitudinal assessment of patient reported outcome measurements. Therefore, DuTOC will play a crucial role in the improvement of the care for patients with thoracic malignancies.

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DuTOC：前瞻性荷兰胸部肿瘤队列：一个全国性的基础设施，用于收集临床数据、PROMS和生物材料，以支持胸部肿瘤研究

荷兰胸部肿瘤队列（DuTOC）是一个全国性的胸部恶性肿瘤患者队列，在患者知情同意后收集患者特征、生活质量和生物材料。有了这些数据和材料，DuTOC为涉及治疗、（分子）诊断、质量控制、生物标志物和转化研究以及生活质量的回顾性和前瞻性研究提供了坚实的基础。DuTOC由荷兰肺科医师协会发起，是参与癌症护理的所有临床医生和胸部恶性肿瘤领域的其他利益相关者（如患者倡导、卫生监管机构、癌症登记和制药公司）的合作。DuTOC的目标是实现实时数据采集的自动化。这最大限度地减少了研究人员的工作量，促进了向基于实时数据的自学医疗保健系统的过渡，并结合了对患者报告的结果测量的长期纵向评估。因此，DuTOC将对改善胸部恶性肿瘤患者的护理起到至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lung Cancer 医学-呼吸系统

CiteScore

9.40

自引率

3.80%

发文量

407

审稿时长

25 days

期刊介绍： Lung Cancer is an international publication covering the clinical, translational and basic science of malignancies of the lung and chest region.Original research articles, early reports, review articles, editorials and correspondence covering the prevention, epidemiology and etiology, basic biology, pathology, clinical assessment, surgery, chemotherapy, radiotherapy, combined treatment modalities, other treatment modalities and outcomes of lung cancer are welcome.