Introducing the Adherence Promotion with Person-centered Technology (APPT) trial: Rationale, methods, and baseline characteristics

IF 1.9 3区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Shenghao Zhang , Michael Dieciuc , Andrew Dilanchian , Mia Liza A. Lustria , Dawn C. Carr , Antonio Terracciano , Zhe He , Shayok Chakraborty , Neil Charness , Walter R. Boot
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Abstract

Home-based cognitive training programs delivered via computers and tablets hold promise as cost-effective, population-level interventions to prevent or mitigate age-related cognitive decline. However, adherence to such programs is often low. Using message-tailoring techniques and an adaptive algorithm, we developed a person-centered reminder smart system that delivers motivational messages at times when participants are predicted to be available for training activities. This paper presents the background, study design, methodology, and baseline data for a randomized controlled trial examining the system's efficacy in supporting adherence to cognitive training. A total of 199 cognitively normal, community-dwelling older adults aged 62 to 88 were randomly assigned (1:1) to either the smart reminder or the control condition. Participants were instructed to engage in training activities for 30 min per day, five days per week, for 18 consecutive weeks. Those in the smart reminder condition received personalized messages, delivered at optimized times, and with targeted content, while those in the control condition received generic messages at a fixed time. Adherence rate will be the primary outcome measure, calculated and compared across conditions. Findings from this study will have implications not only for adherence support in cognitive training but also for broader applications of technology-mediated smart reminder systems, including physical exercise, nutrition, medication management, telehealth, and social connectivity. By enhancing intervention engagement, these systems have the potential to improve the health and well-being of older adults on a large scale.
介绍以人为中心的技术促进依从性试验:基本原理、方法和基线特征
通过电脑和平板电脑提供的以家庭为基础的认知训练项目有望成为具有成本效益的人群干预措施,以预防或减轻与年龄相关的认知能力下降。然而,坚持这样的方案往往很低。利用信息剪裁技术和自适应算法,我们开发了一个以人为中心的提醒智能系统,该系统可以在参与者预计可以参加培训活动时提供激励信息。本文介绍了一项随机对照试验的背景、研究设计、方法和基线数据,该试验检验了该系统在支持坚持认知训练方面的功效。199名认知正常、居住在社区、年龄在62 - 88岁之间的老年人被随机(1:1)分配到智能提醒组和对照组。参与者被要求参加训练活动,每天30分钟,每周五天,连续18周。智能提醒组收到的是个性化的、优化时间的、有针对性的信息,而控制组收到的是固定时间的普通信息。依从率将是主要的结果衡量指标,计算和比较不同条件下的依从率。这项研究的结果不仅对认知训练的依从性支持有影响,而且对技术介导的智能提醒系统的更广泛应用也有影响,包括体育锻炼、营养、药物管理、远程医疗和社会联系。通过加强干预参与,这些系统有可能大规模改善老年人的健康和福祉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
4.50%
发文量
281
审稿时长
44 days
期刊介绍: Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.
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