Lightweight self-attention and deep gated neural network (LSA-DGNet) for multiple neurological disease detection

IF 3.1 4区 生物学 Q2 BIOLOGY
Shraddha Jain , Rajeev Srivastava , Sukomal Pal
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引用次数: 0

Abstract

Detecting neurological diseases is an important task in modern medicine, for which it is crucial to accurately model the temporal distributions of disease genesis. In prior methodologies, temporal patterns are used in feature effects and limiting assumptions such as proportionate risks. We introduce a new methodology for neural disease diagnosis, known as LSA-DGNet (Lightweight Self-Attention based on Deep Gated Network). LSA-DGNet utilizes a deep gated neural network module to model nonlinear and time-lagged effects of variables on disease outcomes. We combined multi-scale time-aware self-attention modules with scaled dot-product self-attention modules so that the parallel structures could provide an integrated self-attention mechanism to improve data perception. LSA-DGNet addresses both issues and, hence, sets a new benchmark for real-time, accurate detection of neurological diseases. Unlike existing approaches, LSA-DGNet integrates a lightweight multi-scale time-aware self-attention mechanism with deep gated neural networks, enabling improved modeling of temporal dependencies in noisy EEG data. This design allows for accurate and efficient detection of multiple neurological diseases, validated on five real-world datasets, setting new benchmarks in classification performance. With up to 250 frames a second, it indicant large progress in computational efficiency—game-changer potential—and clinical applications. The entire framework opens up new opportunities for early diagnosis and more tailored treatment strategies and simply revolutionizes how neurological diseases are detected and treated.
轻量级自我关注和深度门控神经网络(LSA-DGNet)用于多种神经系统疾病检测
神经系统疾病的诊断是现代医学的一项重要任务,准确地建立疾病发生的时间分布模型至关重要。在以前的方法中,时间模式用于特征效果和限制假设,如比例风险。我们介绍了一种新的神经疾病诊断方法,称为LSA-DGNet(基于深度门控网络的轻量级自注意)。LSA-DGNet利用深度门控神经网络模块来模拟变量对疾病结果的非线性和时滞影响。我们将多尺度时间感知自注意模块与尺度点积自注意模块相结合,使并行结构能够提供一个集成的自注意机制,从而提高数据感知能力。LSA-DGNet解决了这两个问题,因此为实时、准确检测神经系统疾病设定了新的基准。与现有方法不同,LSA-DGNet将轻量级多尺度时间感知自注意机制与深度门控神经网络集成在一起,从而改进了噪声脑电图数据中时间依赖性的建模。这种设计可以准确有效地检测多种神经系统疾病,并在五个真实世界的数据集上进行验证,为分类性能设定了新的基准。每秒高达250帧的速度,预示着计算效率的巨大进步——改变游戏规则的潜力——以及临床应用。整个框架为早期诊断和更有针对性的治疗策略开辟了新的机会,并彻底改变了神经系统疾病的检测和治疗方式。
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来源期刊
Computational Biology and Chemistry
Computational Biology and Chemistry 生物-计算机:跨学科应用
CiteScore
6.10
自引率
3.20%
发文量
142
审稿时长
24 days
期刊介绍: Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered. Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered. Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.
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