{"title":"Semi-Supervised Medical Hyperspectral Image Segmentation Using Adversarial Consistency Constraint Learning and Cross Indication Network","authors":"Geng Qin;Huan Liu;Xueyu Zhang;Wei Li;Yuxing Guo;Chuanbin Guo","doi":"10.1109/TIP.2025.3598499","DOIUrl":null,"url":null,"abstract":"Hyperspectral imaging technology is considered a new paradigm for high-precision pathological image segmentation due to its ability to obtain spatial and spectral information of the detected object simultaneously. However, due to the time-consuming and laborious manual annotation, precise annotation of medical hyperspectral images is difficult to obtain. Therefore, there is an urgent need for a semi-supervised learning framework that can fully utilize unlabeled data for medical hyperspectral image segmentation. In this work, we propose an adversarial consistency constraint learning cross indication network (ACCL-CINet), which achieves accurate pathological image segmentation through adversarial consistency constraint learning training strategies. The ACCL-CINet comprises a contextual and structural encoder to form the spatial-spectral feature encoding part. The contextual and structural indications are aggregated into features through a cross indication attention module and finally decoded by a pixel decoder to generate prediction results. For the semi-supervised training strategy, a pixel perceptual consistency module encourages the two models to generate consistent and low-entropy predictions. Secondly, a pixel maximum neighborhood probability adversarial constraint strategy is designed, which produces high-quality pseudo labels for cross supervision training. The proposed ACCL-CINet has been rigorously evaluated on both public and private datasets, with experimental results demonstrating that it outperforms state-of-the-art semi-supervised methods. The code is available at: <uri>https://github.com/Qugeryolo/ACCL-CINet</uri>","PeriodicalId":94032,"journal":{"name":"IEEE transactions on image processing : a publication of the IEEE Signal Processing Society","volume":"34 ","pages":"5414-5428"},"PeriodicalIF":13.7000,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE transactions on image processing : a publication of the IEEE Signal Processing Society","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/11130636/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hyperspectral imaging technology is considered a new paradigm for high-precision pathological image segmentation due to its ability to obtain spatial and spectral information of the detected object simultaneously. However, due to the time-consuming and laborious manual annotation, precise annotation of medical hyperspectral images is difficult to obtain. Therefore, there is an urgent need for a semi-supervised learning framework that can fully utilize unlabeled data for medical hyperspectral image segmentation. In this work, we propose an adversarial consistency constraint learning cross indication network (ACCL-CINet), which achieves accurate pathological image segmentation through adversarial consistency constraint learning training strategies. The ACCL-CINet comprises a contextual and structural encoder to form the spatial-spectral feature encoding part. The contextual and structural indications are aggregated into features through a cross indication attention module and finally decoded by a pixel decoder to generate prediction results. For the semi-supervised training strategy, a pixel perceptual consistency module encourages the two models to generate consistent and low-entropy predictions. Secondly, a pixel maximum neighborhood probability adversarial constraint strategy is designed, which produces high-quality pseudo labels for cross supervision training. The proposed ACCL-CINet has been rigorously evaluated on both public and private datasets, with experimental results demonstrating that it outperforms state-of-the-art semi-supervised methods. The code is available at: https://github.com/Qugeryolo/ACCL-CINet