Kidney transplantation between identical twins with APOL1 homozygote risk alleles - a case report.

Frontiers in nephrology Pub Date : 2025-07-31 eCollection Date: 2025-01-01 DOI:10.3389/fneph.2025.1648263
Sean Lei, Abhirami Shankar, Supreet Sethi, Erik L Lum
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Abstract

Kidney transplantation is the optimal therapy for individuals with end-stage kidney disease. Recent studies suggest a negative impact of high-risk Apolipoprotein L1 genotypes on outcomes for both living kidney donors and kidney transplant recipients. In this case, we describe a pair of identical twins with a high-risk APOL1 genotype who underwent successful living kidney transplantation with excellent short-term outcomes.

具有APOL1纯合子风险等位基因的同卵双胞胎肾移植一例报告。
肾移植是终末期肾病患者的最佳治疗方法。最近的研究表明,高危载脂蛋白L1基因型对活体肾供者和肾移植受者的预后都有负面影响。在这种情况下,我们描述了一对具有高风险APOL1基因型的同卵双胞胎,他们成功地接受了活体肾移植,并获得了良好的短期预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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