Developmental Foundations of a Pediatric Mental Health Risk Calculator for Young Children.

IF 2.8 3区 医学 Q1 PEDIATRICS
Leigha A MacNeill, Yudong Zhang, Gina M Giase, Jillian Lee Wiggins, Elizabeth S Norton, Justin D Smith, Matthew M Davis, Julia G Raven, Roshaye B Poleon, Qiongru Yu, Christopher D Smyser, Cynthia E Rogers, Joan L Luby, Norrina B Allen, Lauren S Wakschlag
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Abstract

Objective: To advance clinical utility of an emerging risk calculator for identifying when to worry and when to act when young children show signs of mental health concerns in pediatric care, we: (1) replicate an early childhood mental health risk algorithm (DECIDE); (2) determine preliminary predictive utility of additional child and parenting assets, advancing a strengths-based framework to reduce the likelihood of biased identification.

Methods: Data were from two independent studies: The national Future of Families and Child Wellbeing Study (FFCWS; N=2,763) and the regional Mental Health, Earlier Synthetic Cohort study (MHESC; N=323). Predictors were assessed in toddlerhood/early preschool age. Internalizing/externalizing problems were measured in older preschoolers, serving as outcomes. Epidemiologic risk prediction methods were applied to: (1) replicate the DECIDE risk algorithm domains comprised of demographics, child irritability, and adverse childhood experiences; and (2) examine the added predictive utility of child and parenting assets. Predictive utility was based on area under the curve (AUC) and/or the integrated discrimination improvement (IDI).

Results: The DECIDE algorithm was replicated in FFCWS and MHESC (AUC=.70 for both studies; IDI=.07 in FFCWS and.06 in MHESC). IDIs indicated predictive utility for child assets beyond the existing DECIDE algorithm in both studies, and for parenting assets in FFCWS.

Conclusions: Robust validation of predictive algorithms is critical for assessing generalizability. Reducing bias in early mental health risk algorithms via a strengths-based approach is key to equitable decision-making. This work lays the foundation for implementation of early mental health decision tools in routine care of young children.

儿童心理健康风险计算器的发展基础。
目的:为了提高一种新兴的风险计算器的临床应用,以确定当幼儿在儿科护理中表现出心理健康问题的迹象时,什么时候该担心,什么时候该采取行动,我们:(1)复制幼儿心理健康风险算法(DECIDE);(2)确定额外的子女和养育资产的初步预测效用,推进基于优势的框架,以减少偏见识别的可能性。方法:数据来自两个独立研究:国家未来家庭和儿童健康研究(FFCWS; N= 2763)和地区心理健康早期综合队列研究(MHESC; N=323)。预测因子在幼儿期/学龄前早期进行评估。内化/外化问题在年龄较大的学龄前儿童中被测量,作为结果。应用流行病学风险预测方法:(1)复制由人口统计学、儿童易怒和不良童年经历组成的decision风险算法域;(2)检验子女和育儿资产的附加预测效用。预测效用基于曲线下面积(AUC)和/或综合判别改进(IDI)。结果:决定算法在FFCWS和MHESC中都是重复的(两项研究的AUC= 0.70;在MHESC中是06)。在这两项研究中,IDIs显示了对子女资产的预测效用,超出了现有的DECIDE算法,以及FFCWS中父母资产的预测效用。结论:预测算法的稳健验证对于评估通用性至关重要。通过基于优势的方法减少早期心理健康风险算法中的偏见是公平决策的关键。这项工作为在幼儿日常护理中实施早期心理健康决策工具奠定了基础。
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来源期刊
Academic Pediatrics
Academic Pediatrics PEDIATRICS-
CiteScore
4.60
自引率
12.90%
发文量
300
审稿时长
60 days
期刊介绍: Academic Pediatrics, the official journal of the Academic Pediatric Association, is a peer-reviewed publication whose purpose is to strengthen the research and educational base of academic general pediatrics. The journal provides leadership in pediatric education, research, patient care and advocacy. Content areas include pediatric education, emergency medicine, injury, abuse, behavioral pediatrics, holistic medicine, child health services and health policy,and the environment. The journal provides an active forum for the presentation of pediatric educational research in diverse settings, involving medical students, residents, fellows, and practicing professionals. The journal also emphasizes important research relating to the quality of child health care, health care policy, and the organization of child health services. It also includes systematic reviews of primary care interventions and important methodologic papers to aid research in child health and education.
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