Meta-Analytic Insights Into Mindfulness Approaches for Depression and Diabetes Comorbidity Care.

Q3 Medicine

Diabetes Spectrum Pub Date : 2025-05-29 eCollection Date: 2025-01-01 DOI:10.2337/ds24-0048

Kenni Wojujutari Ajele, Erhabor Sunday Idemudia

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引用次数: 0

Abstract

Objective: This study evaluated the effectiveness of mindfulness-based interventions (MBIs) in managing comorbid depression and diabetes by assessing their efficacy in reducing depressive symptoms and improving glycemic control, while addressing inconsistencies in existing research.

Research design and methods: A systematic review and meta-analysis were conducted of 17 randomized controlled trials published between 2013 and 2024 and involving 1,336 participants with diabetes and depressive symptoms. Effect sizes were calculated using Hedges' g and random-effects models, with heterogeneity assessed using I ² statistics.

Results: MBIs significantly reduced depressive symptoms (standardized mean difference [SMD] -0.88, 95% CI -1.34 to -0.42) with high heterogeneity (I ² = 90%) and improved A1C levels (SMD -0.23, 95% CI -0.38 to -0.08). Among intervention types, mindfulness-based stress reduction (SMD -1.02, 95% CI -1.57 to -0.48) and mindfulness-based cognitive therapy (SMD -0.92, 95% CI -1.45 to -0.39) showed strong effects. Effects varied by region, with Asian studies showing greater benefits (SMD -1.44) compared with North American studies (SMD -0.61).

Conclusion: MBIs are effective in reducing depressive symptoms and improving glycemic control in individuals with comorbid diabetes and depression. These findings highlight the importance of culturally adapted approaches and call for further research to refine MBI applications in diabetes care.

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抑郁症和糖尿病共病护理的正念方法的元分析见解。

目的：本研究通过评估正念干预（mbi）在减轻抑郁症状和改善血糖控制方面的功效，同时解决现有研究中的不一致之处，评估了mbi在治疗抑郁症和糖尿病共病中的有效性。研究设计和方法：对2013年至2024年间发表的17项随机对照试验进行了系统回顾和荟萃分析，涉及1336名糖尿病和抑郁症状的参与者。使用Hedges' g和随机效应模型计算效应量，使用i2统计量评估异质性。结果：mbi显著减轻抑郁症状（标准化平均差[SMD] -0.88, 95% CI -1.34至-0.42），异质性高（i2 = 90%），改善A1C水平（SMD -0.23, 95% CI -0.38至-0.08）。在干预类型中，正念减压（SMD -1.02, 95% CI -1.57 ~ -0.48）和正念认知疗法（SMD -0.92, 95% CI -1.45 ~ -0.39）表现出较强的效果。效果因地区而异，与北美研究（SMD -0.61）相比，亚洲研究显示更大的益处（SMD -1.44）。结论：MBIs可有效减轻糖尿病合并抑郁症患者的抑郁症状，改善血糖控制。这些发现强调了文化适应方法的重要性，并呼吁进一步研究以完善MBI在糖尿病护理中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes Spectrum Medicine-Internal Medicine

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： The mission of Diabetes Spectrum: From Research to Practice is to assist health care professionals in the development of strategies to individualize treatment and diabetes self-management education for improved quality of life and diabetes control. These goals are achieved by presenting review as well as original, peer-reviewed articles on topics in clinical diabetes management, professional and patient education, nutrition, behavioral science and counseling, educational program development, and advocacy. In each issue, the FROM RESEARCH TO PRACTICE section explores, in depth, a diabetes care topic and provides practical application of current research findings.