Prevalence and spatial distribution of Toxoplasma gondii infection in domestic and stray cats (Felis catus) in Northwestern São Paulo, Brazil

IF 1.7 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Spatial and Spatio-Temporal Epidemiology Pub Date : 2025-08-01 DOI:10.1016/j.sste.2025.100740

Fernando Henrique Antunes Murata , Jéssica Priscilla Barboza , Fernanda Follis Tasso , Tainara Souza Pinho , Tiago Henrique , Janine Fusco Alves , FAMERP Toxoplasma Research Group , Carlos Alexandre Guimarães de Souza , Daniel Abrahão , Ubirajara Leoncy de Lavor , Chunlei Su , Luiz Carlos de Mattos , Cinara Cássia Brandão

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引用次数: 0

Abstract

Toxoplasmosis is a zoonotic disease caused by the apicomplexan parasite Toxoplasma gondii, that can infect any warm-blooded animal, including mammals and birds. Felids are the definitive hosts, with infected cats capable of shedding millions of resistant oocysts into the environment. This study aimed to evaluate the seroprevalence and geospatial distribution of T. gondii infection in pet and stray cats attended at the Zoonosis Control Center in São José do Rio Preto, northwest São Paulo, Brazil. Anti-T. gondii antibodies were detected in 36 (25.2 %) of 143 pet cats and 85 (27.8 %) of 306 stray cats, with an overall prevalence of 26.9 %. Male pet cats exhibited a significantly higher risk of infection compared to females (19.5 % vs 34.5 %; p = 0.045). Regional analysis revealed significant difference in seroprevalence between four regions (HB vs Bosque for pet cats, p = 0.035, and Cidade da Criança vs Central for stray cats, p = 0.040). Spatial cluster analysis identified 27 significant hotspots and 70 coldspots (p ≤ 0.05) throughout the municipality. This study represents the first investigation of the seroprevalence and geospatial distribution of T. gondii infection in domestic and stray cats within this region, providing valuable information on the epidemiology of T. gondii. These findings contribute to a better understanding of the transmission dynamics of T. gondii, supporting the development of effective prevention strategies and reinforcing the importance of a One Health approach.

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巴西圣保罗西北部地区家猫和流浪猫刚地弓形虫感染流行及空间分布

弓形虫病是一种由弓形虫引起的人畜共患疾病，它可以感染任何温血动物，包括哺乳动物和鸟类。猫科动物是最终宿主，受感染的猫能够向环境中释放数百万个具有抗性的卵囊。本研究旨在评估巴西圣保罗西北部 o joss do里约热内卢Preto人畜共患病控制中心接待的宠物和流浪猫中弓形虫感染的血清阳性率和地理空间分布。Anti-T。143只宠物猫中检出弓形虫抗体36只（25.2%），306只流浪猫中检出弓形虫抗体85只（27.8%），总体检出率为26.9%。与雌性相比，雄性宠物猫的感染风险明显更高（19.5% vs 34.5%; p = 0.045）。区域分析显示，四个地区（宠物猫HB vs博斯克，p = 0.035，流浪猫Cidade da criana vs Central， p = 0.040）的血清患病率存在显著差异。空间聚类分析发现全市有27个显著热点和70个显著冷点（p≤0.05）。本研究首次调查了该地区家猫和流浪猫中弓形虫感染的血清流行率和地理空间分布，为弓形虫流行病学研究提供了有价值的信息。这些发现有助于更好地了解弓形虫的传播动态，支持制定有效的预防战略，并加强“同一个健康”方针的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Spatial and Spatio-Temporal Epidemiology PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

5.10

自引率

8.80%

发文量