Prevalence of Isolated Iliac Aneurysm in Patients with Acute Aortic Dissection

IF 1.6 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

Annals of vascular surgery Pub Date : 2025-08-14 DOI:10.1016/j.avsg.2025.07.036

Xinyang Li , Chong Liu , Chuanjiang Wang , Haidi Hu

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Abstract

Background

The relationship between isolated iliac aneurysms (IIAs) and acute aortic dissection (AAD) is uncertain. We aimed to determine the prevalence of IIAs in patients with AAD and evaluate the independent risk factors for the presence of IIAs in them.

Methods

Seven patients were confirmed to have AAD with IIAs (AAD + IIA group) who had undergone computed tomography angiography (CTA). The control group comprised 597 patients were confirmed with AAD without IIAs (AAD group). Demographic data or baseline characteristics of patients included in this study were completely obtained. Two readers reviewed all CTA scans independently to assess the data of the IIAs. Baseline characteristics were compared between the aortic dissection group and the control group using propensity score matching, and logistic regression analysis was performed to determine the independent risk factors for the presence of IIAs.

Results

The average age was 67.57 ± 10.13 years in the AAD + IIA group and 52.09 ± 12.06 years in the AAD group (P = 0.002). The proportion of smokers was respectively 39.6% and 85.7% in the AAD group and AAD + IIA group (P = 0.037). In the control group, no difference in age was observed between the dissections from the aorta to the iliac artery (n = 251 [42%]; 51.08 ± 11.35 years) and those limited to the aortic region (n = 346 [58%]; 52.82 ± 12.51 years) (P = 0.055). Multivariate analysis revealed age as an independent risk factor for the presence of IIAs (odds ratio, 1.144; 95% confidence interval, 1.059–1.235; P = 0.001). Similarly, smoking was an independent risk factor for the presence of IIAs (odds ratio, 14.601; 95% confidence interval, 1.652–129.073; P = 0.016).

Conclusion

The prevalence of IIA in AAD was 1.2%. Age and smoking can increase the prevalence of IIAs in patients with AAD. Our results can represent a valid aid in selecting patients to be screened, which would improve the treatment outcome. Further prospective studies are warranted to demonstrate the substantial prevalence of IIAs in the AAD population.

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急性主动脉夹层患者孤立性髂动脉瘤的患病率。

背景：孤立性髂动脉瘤（IIAs）与急性主动脉夹层（AAD）之间的关系尚不确定。我们的目的是确定AAD患者中IIAs的患病率，并评估其中存在IIAs的独立危险因素。方法：7例确诊为AAD合并IIA的患者（AAD+IIA组）行计算机断层血管造影（CTA）。对照组597例确诊为AAD，无IIAs （AAD组）。本研究纳入的患者的人口学数据或基线特征被完全获得。两位读者独立审查了所有CTA扫描以评估iia的数据。采用倾向评分匹配比较主动脉夹层组和对照组的基线特征，并进行logistic回归分析以确定iia存在的独立危险因素。结果：AAD+IIA组平均年龄67.57±10.13岁，AAD组平均年龄52.09±12.06岁（P=0.002）。AAD组和AAD+IIA组吸烟者比例分别为39.6%和85.7% （P=0.037）。在对照组中，从主动脉到髂动脉的夹层在年龄上没有差异(n=251例[42%]；51.08±11.35年)和局限于主动脉区域的患者(n=346 [58%]；52.82±12.51岁)（P=0.055）。多因素分析显示，年龄是iia存在的独立危险因素(优势比，1.144；95%置信区间为1.059 ~ 1.235；P = 0.001)。同样，吸烟是iia存在的独立危险因素(优势比，14.601；95%置信区间为1.652-129.073；P = 0.016)。结论：AAD患者中IIA患病率为1.2%。年龄和吸烟可增加AAD患者中ias的患病率。我们的结果可以代表一个有效的辅助选择患者进行筛选，这将改善治疗效果。进一步的前瞻性研究有必要证明iia在AAD人群中的普遍存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of vascular surgery 医学-外科

CiteScore

3.00

自引率

13.30%

发文量

603

审稿时长

50 days

期刊介绍： Annals of Vascular Surgery, published eight times a year, invites original manuscripts reporting clinical and experimental work in vascular surgery for peer review. Articles may be submitted for the following sections of the journal: Clinical Research (reports of clinical series, new drug or medical device trials) Basic Science Research (new investigations, experimental work) Case Reports (reports on a limited series of patients) General Reviews (scholarly review of the existing literature on a relevant topic) Developments in Endovascular and Endoscopic Surgery Selected Techniques (technical maneuvers) Historical Notes (interesting vignettes from the early days of vascular surgery) Editorials/Correspondence