Li Zhang, Yu Zeng, Yange Sun, Chengyi Zheng, Yan Feng, Huaping Guo
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引用次数: 0
Abstract
Automated polyp detection plays a critical role in the early diagnosis of colorectal cancer, ranking as the second leading cause of cancer-related mortality worldwide. However, existing segmentation methods face difficulties in handling complex polyp shapes, size variations, and generalising across diverse datasets. We propose a Multi-dimensional Residual Attention Network (MRANet) for the polyp segmentation task, focusing on enhancing feature representation and ensuring robust performance across diverse clinical scenarios. During encoding, MRANet employs residual self-attention to capture semantic information of high-level features, guiding the refinement of low-level information. In addition, convolutions with Multiple Kernel and Dilation rates (CMKD) are integrated with residual channel and spatial attentions to expand the model's receptive field, enhance encoder features, and accelerate convergence. In the decoding stage, MRANet uses the proposed Attention-based Scale Interaction Module (ASIM) to merge upsampled high-level features with low-level pixel information, enriching low-level layers using semantic knowledge. A Residual-based Scale Fusion Module (RSFM) is further designed to merge low-level features, which preserves high-frequency details including edges and textures. Experiments demonstrate that MRANet effectively segments polyps with varying sizes, indistinct boundaries, and scattered distributions, achieving the best overall performance. Our code is available at https://github.com/hpguo1982/MRANet.
期刊介绍:
IET Systems Biology covers intra- and inter-cellular dynamics, using systems- and signal-oriented approaches. Papers that analyse genomic data in order to identify variables and basic relationships between them are considered if the results provide a basis for mathematical modelling and simulation of cellular dynamics. Manuscripts on molecular and cell biological studies are encouraged if the aim is a systems approach to dynamic interactions within and between cells.
The scope includes the following topics:
Genomics, transcriptomics, proteomics, metabolomics, cells, tissue and the physiome; molecular and cellular interaction, gene, cell and protein function; networks and pathways; metabolism and cell signalling; dynamics, regulation and control; systems, signals, and information; experimental data analysis; mathematical modelling, simulation and theoretical analysis; biological modelling, simulation, prediction and control; methodologies, databases, tools and algorithms for modelling and simulation; modelling, analysis and control of biological networks; synthetic biology and bioengineering based on systems biology.