Xiaonan Du, Taipu Guo, Shuaijie Pei, Yue Yang, Keliang Xie
{"title":"Changes in right heart load in patients with ARDS and the benefits of prone ventilation.","authors":"Xiaonan Du, Taipu Guo, Shuaijie Pei, Yue Yang, Keliang Xie","doi":"10.1016/j.amjms.2025.08.007","DOIUrl":null,"url":null,"abstract":"<p><p>Acute respiratory distress syndrome (ARDS) often occurs in the intensive care unit, and patients with ARDS have a poor prognosis due to severe hypoxemia caused by bilateral pulmonary oedema. Moreover, circulatory problems in patients with ARDS are a major concern for intensive care unit physicians. Due to increased pulmonary circulatory resistance, patients with acute respiratory distress syndrome usually exhibit increased right heart afterload, and patients with right heart failure usually develop Acute cor pulmonale(ACP). Prone ventilation is a common treatment for moderate-to-severe acute respiratory distress syndrome, and the prone position not only improves the patient's oxygenation index but also reduces pulmonary circulatory resistance and relieves circulatory pressure through multiple pathways. This article summarises the factors that increase pulmonary circulatory resistance in patients with ARDS and the circulatory benefits of prone ventilation. The purpose of this study was to provide assistance in the management of patients with ARDS.</p>","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of the medical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.amjms.2025.08.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Acute respiratory distress syndrome (ARDS) often occurs in the intensive care unit, and patients with ARDS have a poor prognosis due to severe hypoxemia caused by bilateral pulmonary oedema. Moreover, circulatory problems in patients with ARDS are a major concern for intensive care unit physicians. Due to increased pulmonary circulatory resistance, patients with acute respiratory distress syndrome usually exhibit increased right heart afterload, and patients with right heart failure usually develop Acute cor pulmonale(ACP). Prone ventilation is a common treatment for moderate-to-severe acute respiratory distress syndrome, and the prone position not only improves the patient's oxygenation index but also reduces pulmonary circulatory resistance and relieves circulatory pressure through multiple pathways. This article summarises the factors that increase pulmonary circulatory resistance in patients with ARDS and the circulatory benefits of prone ventilation. The purpose of this study was to provide assistance in the management of patients with ARDS.