Anesthesia Management of a Patient With Common Variable Immunodeficiency and End-stage Liver Disease Undergoing Laparoscopic Surgery: A Case Report.

Abstract

Common variable immunodeficiency (CVID) is one of the most common forms of severe primary immunodeficiency, characterized by a deficiency of immunoglobulin G (IgG) and impaired antibody responses, which increase susceptibility to infections. Anesthetic management of patients with CVID and end-stage liver disease is extremely challenging for anesthesiologists. We report the successful anesthesia management of a 46-year-old female patient with end-stage liver disease, diagnosed with CVID at age 26, by applying timely intravenous immunoglobulin and prophylactic antibiotic therapy for laparoscopic cholecystectomy and hernia repair surgery. Increasing knowledge and awareness of perioperative staff, along with a comprehensive preoperative evaluation, is important in caring for patients with CVID, contributing significantly to preoperative preparation, intraoperative monitoring, and postoperative recovery, as well as ensuring patient safety and optimizing outcomes.