Rhodium-Catalyzed Hydroselenation of Unsymmetric 1,3-Dienes with 3,4-Markovnikov Regioselectivity

IF 4.7 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Chemistry Frontiers Pub Date : 2025-08-14 DOI:10.1039/d5qo00926j

Anee Taj, Chen Cui, Zhenwei Shi, Xuebin Huang, Xiao-Hui Yang

引用次数: 0

Abstract

Catalytic hydroselenation of alkenes represents one of the most direct and efficient methods for organoselenide synthesis. In this study, we report a highly regioselective Rh-catalyzed hydroselenation of unsymmetrical 1,3-dienes, including internalunsymmetrical dienes. This atom-economical method operates under mild conditions and selectively affords 3,4-Markovnikov products with excellent regiocontrol. The developed protocol was effective in reactions involving both internal and terminal dienes.

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铑催化具有3,4- markovnikov区选择性的不对称1,3-二烯的加氢硒化反应

烯烃催化硒化反应是合成有机硒化物最直接、最有效的方法之一。在这项研究中，我们报道了一个高度区域选择性的铑催化的不对称的1,3-二烯的氢硒化反应，包括内部不对称的二烯。这种原子经济的方法在温和的条件下运行，选择性地提供3,4- markovnikov产物，具有良好的区域控制。开发的协议是有效的反应涉及内部和末端二烯。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.