Effectiveness of double-layer artificial dermis repair material combined with autologous skin patch in repairing deep skin and soft tissue defects: a retrospective study.

Abstract

Objectives: With the development of biotechnology, double-layer artificial dermis repair material has been increasingly employed to repair deep skin and soft tissue defects. This study aims to investigate the effectiveness of double-layer artificial dermis repair material combined with autologous skin patch in repairing deep skin and soft tissue defects.

Methods: This study conducted a retrospective analysis of 18 patients with deep skin and soft tissue defects who were treated with a combination of double-layer artificial dermal repair materials and autologous skin grafting at our hospital between January 2022 and January 2024.

Results: A total of 18 patients were treated, including 7 males and 11 females, with an average age of 41.7 ± 19.12 years. All patients exhibited good vascularization of the double-layer artificial dermal material postoperatively. In one patient, only a small part of the autologous skin patch survived after the first grafting, and the skin healed well after the second grafting. The remaining patients healed well after the operation. Two months after the operation, the results showed that no obvious hyperplastic contracture scar was found in the wound grafts of 18 patients, and the total Vancouver Scar Scale (VSS) score was not significantly different between 1 month and 2 months after the operation (p > 0.05).

Conclusion: Double-layer artificial dermis repair material combined with autologous skin patch provides a reliable, less invasive and simple treatment for deep skin and soft tissue defects.