Assessing the impact of air pollution exposure on preterm birth risk in different subtypes of twin pregnancies and identifying critical sensitive windows.
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引用次数: 0
Abstract
Recent studies on maternal exposure to air pollution and preterm birth (PTB) have yielded inconsistent results, with varying critical windows of exposure. This study aims to explore the association between air pollution and the risk of preterm birth in different subtypes of twin pregnancies, while identifying the sensitive time windows. In this retrospective study, we analyzed 3623 twin-pregnant women, categorized by timing and clinical condition of preterm birth. We used restricted cubic splines (RCS) and multivariable logistic regression to examine the effects of air pollution on different preterm birth subtypes. The results indicate that air pollution exposure during twin pregnancy significantly increased the risk of late-PTB and sPTB. In the third trimester, exposure to PM2.5, PM10, SO2, NO2, and CO increased the risk of late-PTB. Six pollutants were associated with higher sPTB risk throughout pregnancy, particularly in late pregnancy, with more pronounced increase. These results suggest that late pregnancy may be a critical window for the impacts of air pollution on twin pregnancies. These findings provide important scientific evidence to manage air pollution-related PTB risks in twin pregnancy.
期刊介绍：
Environmental Geochemistry and Health publishes original research papers and review papers across the broad field of environmental geochemistry. Environmental geochemistry and health establishes and explains links between the natural or disturbed chemical composition of the earth’s surface and the health of plants, animals and people.
Beneficial elements regulate or promote enzymatic and hormonal activity whereas other elements may be toxic. Bedrock geochemistry controls the composition of soil and hence that of water and vegetation. Environmental issues, such as pollution, arising from the extraction and use of mineral resources, are discussed. The effects of contaminants introduced into the earth’s geochemical systems are examined. Geochemical surveys of soil, water and plants show how major and trace elements are distributed geographically. Associated epidemiological studies reveal the possibility of causal links between the natural or disturbed geochemical environment and disease. Experimental research illuminates the nature or consequences of natural or disturbed geochemical processes.
The journal particularly welcomes novel research linking environmental geochemistry and health issues on such topics as: heavy metals (including mercury), persistent organic pollutants (POPs), and mixed chemicals emitted through human activities, such as uncontrolled recycling of electronic-waste; waste recycling; surface-atmospheric interaction processes (natural and anthropogenic emissions, vertical transport, deposition, and physical-chemical interaction) of gases and aerosols; phytoremediation/restoration of contaminated sites; food contamination and safety; environmental effects of medicines; effects and toxicity of mixed pollutants; speciation of heavy metals/metalloids; effects of mining; disturbed geochemistry from human behavior, natural or man-made hazards; particle and nanoparticle toxicology; risk and the vulnerability of populations, etc.
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