Bioimpedance a Diagnostic Tool for Tobacco-induced Oral Lesions - A Mixed Model Cross-sectional Study.

IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Contemporary Clinical Dentistry Pub Date : 2025-04-01 Epub Date: 2025-07-14 DOI:10.4103/ccd.ccd_290_24

Vaibhav Gupta, Poonam Goel, Usha Agrawal, Neena Chaudhary, Garima Jain, Deepak Gupta

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引用次数: 0

Abstract

Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysplasia, prostate cancer, breast cancer, and basal cell carcinoma. The current study aimed to validate and evaluate bioimpedance as a diagnostic tool for tobacco-induced oral lesions.

Methodology: The study comprised 50 oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs) tissue specimens for in vitro study and 320 subjects for in vivo study. Bioimpedance device prepared and calibrated. EIS measurements were done for the habit and control groups and were compared.

Results: The impedance value in the control group was significantly higher compared to the OPMD and OSCC groups. Diagnosis based on bioimpedance spectroscopy measurements has a sensitivity of 95.9% and a specificity of 86.7%.

Conclusion: Bioimpedance device can help in decision-making for differentiating OPMD and OSCC cases and their management, especially in primary healthcare settings.

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生物阻抗是烟草诱发口腔病变的诊断工具-一项混合模型横断面研究。

电阻抗谱（EIS）是近年来发展起来的一种用于筛查和评估宫颈发育不良、前列腺癌、乳腺癌和基底细胞癌的新型诊断设备。目前的研究旨在验证和评估生物阻抗作为烟草引起的口腔病变的诊断工具。方法：该研究包括50例口腔鳞状细胞癌（OSCC）和口腔潜在恶性疾病（OPMDs）组织标本进行体外研究，320例受试者进行体内研究。制备并校准了生物阻抗装置。对习惯组和对照组进行EIS测量并进行比较。结果：对照组的阻抗值明显高于OPMD和OSCC组。基于生物阻抗谱测量的诊断灵敏度为95.9%，特异性为86.7%。结论：生物阻抗装置有助于OPMD和OSCC的鉴别和治疗决策，特别是在初级卫生保健机构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Contemporary Clinical Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

23 weeks

期刊介绍： The journal Contemporary Clinical Dentistry (CCD) (Print ISSN: 0976-237X, E-ISSN:0976- 2361) is peer-reviewed journal published on behalf of Maharishi Markandeshwar University and issues are published quarterly in the last week of March, June, September and December. The Journal publishes Original research papers, clinical studies, case series strictly of clinical interest. Manuscripts are invited from all specialties of Dentistry i.e. Conservative dentistry and Endodontics, Dentofacial orthopedics and Orthodontics, Oral medicine and Radiology, Oral pathology, Oral surgery, Orodental diseases, Pediatric Dentistry, Periodontics, Clinical aspects of Public Health dentistry and Prosthodontics. Review articles are not accepted. Review, if published, will only be by invitation from eminent scholars and academicians of National and International repute in the field of Medical/Dental education.