Charcot foot disease: A new approach.

IF 3.8 3区 医学 Q2 GERIATRICS & GERONTOLOGY
Drugs & Aging Pub Date : 2025-09-01 Epub Date: 2025-08-11 DOI:10.1007/s40266-025-01234-0
Michal Dubský, Robert Bém, Dominika Sojáková, Vladimira Fejfarová, Michael Hughes, Edward B Jude
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引用次数: 0

Abstract

Charcot neuropathic osteoarthropathy (CNO) is a condition that develops in the presence of neuropathy, most commonly diabetes-related neuropathy. Owing to the neuropathy, microtrauma to the bones occur without the individual feeling them. With continued walking, bone inflammation, resorption, microfractures and structural changes occur in the bones, which result in irreversible deformities. Diagnosing this condition is often difficult and requires advanced imaging techniques, such as scintigraphy or magnetic resonance imaging, as X-ray changes may not be specific. Treatment of CNO includes immobilization, offloading, recalcification (supplementation of vitamin D and calcium) and in the most advanced cases, surgical treatment. This narrative review aims to synthesize the recent research and clinical implications relating to Charcot foot to help healthcare professionals to stay up-to-date in this relevant topic.

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夏足病:一种新方法。
Charcot神经性骨关节病(CNO)是一种在神经病变存在下发展的疾病,最常见的是糖尿病相关的神经病变。由于神经病变,对骨骼的微创伤在个体感觉不到的情况下发生。随着持续行走,骨骼会发生炎症、骨吸收、微骨折和结构变化,导致不可逆的畸形。诊断这种疾病通常很困难,需要先进的成像技术,如闪烁成像或磁共振成像,因为x射线的变化可能不是特异性的。CNO的治疗包括固定、卸载、钙化(补充维生素D和钙),在大多数晚期病例中,手术治疗。这篇叙述性综述的目的是综合最近的研究和临床意义有关夏科足,以帮助医疗保健专业人员保持最新的在这个相关的主题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drugs & Aging
Drugs & Aging 医学-老年医学
CiteScore
5.50
自引率
7.10%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Drugs & Aging delivers essential information on the most important aspects of drug therapy to professionals involved in the care of the elderly. The journal addresses in a timely way the major issues relating to drug therapy in older adults including: the management of specific diseases, particularly those associated with aging, age-related physiological changes impacting drug therapy, drug utilization and prescribing in the elderly, polypharmacy and drug interactions.
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