Intraosseous schwannoma of the olecranon: A case report.

IF 1.9 Q2 ORTHOPEDICS
Ömer Faruk Naldöven, Nevzat Arıcan, Şahan Güven, Servet Güreşci, Şahin Çepni
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Abstract

Intraosseous schwannomas are extremely rare benign tumors originating from Schwann cells of the peripheral nervous system. While these tumors are commonly found in the mandible and sacrum, their occurrence in long bones, particularly the ulna, is uncommon. A 59-year-old female patient was admitted with a two-year history of pain and swelling in her right elbow. Radiographic imaging revealed a lytic lesion with cortical expansion and thinning in the proximal ulna metaphysis, while magnetic resonance imaging showed a lesion with irregular borders extending into the joint via cortical erosion. Differential diagnoses included a simple bone cyst, enchondroma, giant cell tumor, and metastasis. Surgical procedure involved curettage and bone grafting, and the lesion was diagnosed histologically as an intraosseous schwannoma. Immunohistochemical staining showed positive expression of SOX10 and S100, confirming the diagnosis. Postoperative recovery was uneventful, and the patient regained a full range of motion without pain at her six-month follow-up. In conclusion, this case underscores the importance of considering intraosseous schwannoma in the differential diagnosis of benign bone lesions, particularly in rare locations such as the ulna. Histopathological examination remains essential for an accurate diagnosis.

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鹰嘴骨内神经鞘瘤1例。
骨内神经鞘瘤是一种极为罕见的良性肿瘤,起源于周围神经系统的雪旺细胞。虽然这些肿瘤常见于下颌骨和骶骨,但它们发生在长骨,特别是尺骨,是罕见的。59岁女性患者因右肘疼痛和肿胀两年入院。x线影像学显示尺骨近端干骺端皮质扩张和变薄的溶解性病变,而磁共振成像显示不规则边界病变通过皮质侵蚀延伸到关节。鉴别诊断包括单纯性骨囊肿、内生纤维瘤、巨细胞瘤和转移。手术包括刮除和植骨,病理诊断为骨内神经鞘瘤。免疫组化染色显示SOX10和S100阳性表达,证实诊断。术后恢复顺利,患者在6个月的随访中恢复了全活动能力,无疼痛。总之,这个病例强调了在良性骨病变鉴别诊断中考虑骨内神经鞘瘤的重要性,特别是在罕见的部位,如尺骨。组织病理学检查仍然是准确诊断的必要条件。
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