Relationship of malnutrition and frailty on prolonged stay at the hospital in heart failure patients

IF 3.7 2区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

ESC Heart Failure Pub Date : 2025-08-11 DOI:10.1002/ehf2.15390

Katarzyna Lomper, Maria Jędrzejczyk, Marta Wleklik, Izabella Uchmanowicz

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Abstract

Background

Nutritional status is a critical determinant of clinical outcomes in patients with chronic heart failure (CHF), potentially contributing to adverse prognosis and suboptimal therapeutic response. Despite growing interest, the interplay between malnutrition and frailty syndrome (FS) in the CHF population remains inadequately elucidated.

Aims

The study aims to evaluate the association between malnutrition risk and the presence of FS in individuals hospitalized with CHF.

Methods

A total of 200 patients (mean age: 72.28 years) hospitalized due to CHF were enrolled. Data collection included retrospective analysis of medical records and application of validated instruments: the Mini Nutritional Assessment (MNA) for nutritional evaluation and the Fried phenotype criteria for frailty assessment.

Results

Based on MNA, 63.5% of participants demonstrated normal nutritional status, 35.0% were at risk of malnutrition and 1.5% were malnourished (mean MNA score: 24.25). According to the Fried phenotype, 35% were classified as pre-frail and 65% as frail (mean frailty score: 2.67). A statistically significant association was identified between MNA score and frailty status (P < 0.05), with the highest prevalence of frailty observed in malnourished individuals (P = 0.002). No significant correlations were found between frailty and anthropometric parameters such as calf circumference (P = 0.17), arm circumference (P = 0.687) or body mass index (BMI) (P = 0.643).

Conclusions

These findings highlight the clinical importance of routine, comprehensive nutritional screening in patients with CHF. Early identification and management of malnutrition may play a pivotal role in mitigating frailty and enhancing clinical outcomes in this high-risk population.

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心力衰竭患者长期住院期间营养不良与虚弱的关系

背景：营养状况是慢性心力衰竭（CHF）患者临床结局的关键决定因素，可能导致不良预后和治疗反应不佳。尽管越来越多的兴趣，营养不良和虚弱综合征（FS）之间的相互作用在CHF人群仍然没有充分阐明。目的：本研究旨在评估慢性心力衰竭住院患者营养不良风险与FS存在之间的关系。方法：纳入200例因CHF住院的患者，平均年龄72.28岁。数据收集包括对医疗记录的回顾性分析和有效工具的应用：用于营养评估的Mini营养评估（MNA）和用于虚弱评估的Fried表型标准。结果：根据MNA， 63.5%的参与者表现出正常的营养状况，35.0%的人有营养不良的风险，1.5%的人营养不良（MNA平均得分：24.25）。根据Fried表型，35%的人被分类为虚弱前期，65%的人被分类为虚弱（平均虚弱评分：2.67）。结论：这些发现强调了常规、全面的CHF患者营养筛查的临床重要性。在这一高危人群中，营养不良的早期识别和管理可能在减轻虚弱和提高临床结果方面发挥关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ESC Heart Failure Medicine-Cardiology and Cardiovascular Medicine

CiteScore

7.00

自引率

7.90%

发文量

461

审稿时长

12 weeks

期刊介绍： ESC Heart Failure is the open access journal of the Heart Failure Association of the European Society of Cardiology dedicated to the advancement of knowledge in the field of heart failure. The journal aims to improve the understanding, prevention, investigation and treatment of heart failure. Molecular and cellular biology, pathology, physiology, electrophysiology, pharmacology, as well as the clinical, social and population sciences all form part of the discipline that is heart failure. Accordingly, submission of manuscripts on basic, translational, clinical and population sciences is invited. Original contributions on nursing, care of the elderly, primary care, health economics and other specialist fields related to heart failure are also welcome, as are case reports that highlight interesting aspects of heart failure care and treatment.