{"title":"The role of vitamin C on the skin.","authors":"Lehlohonolo Makhakhe","doi":"10.4102/safp.v67i1.6098","DOIUrl":null,"url":null,"abstract":"<p><p>Vitamin C (ascorbic acid or ascorbate) plays an important role in regulating the health of the skin, promoting the differentiation of epithelial skin cells (keratinocytes) while contributing a notable role in the reduction of melanin synthesis, leading to antioxidative protection against solar-related skin damage. Vitamin C is only sourced from diet because humans have no ability to synthesise it in vivo. Routine dietary intake choices become key in maintaining the skin's integrity, preventing and treating some of the skin conditions encountered regularly by general practitioners and skin specialists alike. There is a strong association between vitamin C and the ageing process, skin pigmentation, control of certain skin diseases and a role in some skin cancers through antioxidation properties. Literature suggests that topical application of vitamin C in different forms of formulations has been demonstrated to have more clinical effect than oral intake.Contribution: This article spotlights the benefits of a vitamin commonly encountered in topical pharmaceutics, ingested as tablets or as part of our routine diet.</p>","PeriodicalId":22040,"journal":{"name":"South African Family Practice","volume":"67 1","pages":"e1-e7"},"PeriodicalIF":1.4000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339815/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"South African Family Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4102/safp.v67i1.6098","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Vitamin C (ascorbic acid or ascorbate) plays an important role in regulating the health of the skin, promoting the differentiation of epithelial skin cells (keratinocytes) while contributing a notable role in the reduction of melanin synthesis, leading to antioxidative protection against solar-related skin damage. Vitamin C is only sourced from diet because humans have no ability to synthesise it in vivo. Routine dietary intake choices become key in maintaining the skin's integrity, preventing and treating some of the skin conditions encountered regularly by general practitioners and skin specialists alike. There is a strong association between vitamin C and the ageing process, skin pigmentation, control of certain skin diseases and a role in some skin cancers through antioxidation properties. Literature suggests that topical application of vitamin C in different forms of formulations has been demonstrated to have more clinical effect than oral intake.Contribution: This article spotlights the benefits of a vitamin commonly encountered in topical pharmaceutics, ingested as tablets or as part of our routine diet.
期刊介绍：
South African Family Practice (SAFP) is a peer-reviewed scientific journal, which strives to provide primary care physicians and researchers with a broad range of scholarly work in the disciplines of Family Medicine, Primary Health Care, Rural Medicine, District Health and other related fields. SAFP publishes original research, clinical reviews, and pertinent commentary that advance the knowledge base of these disciplines. The content of SAFP is designed to reflect and support further development of the broad basis of these disciplines through original research and critical review of evidence in important clinical areas; as well as to provide practitioners with continuing professional development material.
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