Access to Limited Critical Care and Risk of Mortality in Rwanda: A Prospective Cohort Study.

IF 2.7 Q4 Medicine
Critical care explorations Pub Date : 2025-08-07 eCollection Date: 2025-08-01 DOI:10.1097/CCE.0000000000001298
Alex Mezei, Donatien Hitayezu, Tyler Gilman, Jeffrey Bone, Celestin Hategaka, Srinivas Murthy, Marla McKnight, Theogene Twagirumugabe
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Abstract

Importance: There is a large discrepancy between need and access to critical care in low- and middle-income countries. Little is known about what subgroups of patients are being prioritized for critical care.

Objectives: The primary objective was to assess what clinical, demographic, and socioeconomic variables were associated with timely ICU admission. Secondary objectives included determining the rate of ICU admission among patients who met admission criteria, inpatient mortality, and length of stay.

Design: Prospective cohort study.

Setting and participants: All adult patients meeting ICU admission criteria at the University Teaching Hospital of Butare, Huye, Rwanda.

Main outcomes and measures: The primary outcome was the proportion of patients admitted to ICU within 24 hours of being identified as critically ill. A multivariable logistic regression model was used to assess whether clinical, demographic, or socioeconomic factors are associated with timely ICU admission. Secondary outcomes were the proportion of patients admitted to ICU at any time, inpatient mortality, and length of stay.

Results: Three hundred eighteen patients were enrolled between January 24, 2024, and June 3, 2024. Eighty-eight (27.7%) were admitted to ICU within 24 hours. Requiring ICU for postoperative recovery (odds ratio [OR], 8.21; 95% CI, 3.64-19.8), obstetric patients (OR, 2.43; 95% CI, 0.92-6.41), and ICU bed availability (OR, 1.26; 95% CI, 1.02-1.55) increased the odds of timely ICU admission in multivariable analysis. Socioeconomic status, gender, and social connections had minimal association with ICU admission, with wide CIs. The inpatient mortality rate was 44.0% and average length of stay was 14 days.

Conclusions and relevance: Obstetric and postoperative patients are prioritized for ICU admission. There is a large unmet need for critical care in Rwanda, and mortality among critically ill patients is high.

Abstract Image

卢旺达获得有限的重症监护和死亡风险:一项前瞻性队列研究。
重要性:在低收入和中等收入国家,重症监护的需求和可及性之间存在很大差异。对于哪些亚组患者优先接受重症监护,人们知之甚少。目的:主要目的是评估哪些临床、人口统计学和社会经济变量与及时入住ICU有关。次要目的包括确定符合入院标准的患者的ICU入院率、住院死亡率和住院时间。设计:前瞻性队列研究。环境和参与者:所有符合卢旺达胡耶市布塔雷大学教学医院ICU入院标准的成年患者。主要结局和措施:主要结局是在确诊为危重患者后24小时内入住ICU的患者比例。采用多变量logistic回归模型评估临床、人口统计学或社会经济因素是否与及时入住ICU相关。次要结局是任何时间入住ICU的患者比例、住院死亡率和住院时间。结果:在2024年1月24日至2024年6月3日期间,共有318名患者入组。88例(27.7%)在24小时内入住ICU。术后恢复需要ICU(优势比[OR], 8.21;95% CI, 3.64-19.8),产科患者(OR, 2.43;95% CI, 0.92-6.41)和ICU床位可用性(OR, 1.26;在多变量分析中,95% CI(1.02-1.55)增加了及时入住ICU的几率。社会经济地位、性别和社会关系与ICU住院的相关性最小,ci范围广。住院死亡率为44.0%,平均住院时间为14天。结论及意义:产科和术后患者优先进入ICU。卢旺达对重症护理的大量需求未得到满足,重症患者的死亡率很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.70
自引率
0.00%
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审稿时长
8 weeks
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