Pyoderma gangrenosum-like ulcer association in small vessel vasculitis (Vasculitis presenting as pyoderma gangrenosum-like ulcer)

Abstract

Pyoderma gangrenosum (PG) was first described by French Dermatologist Louis-Anne-Jean Brocq as a “rapidly spreading ulceration of soft tissue”.¹ Histologically, PG is a neutrophilic dermatosis presenting as painful ulcerations. It is known to be associated with autoimmune-mediated disorders such as vasculitis.² Timely confirmatory diagnosis with tissue biopsy and management with immunosuppressive agents are critical.¹ We report a unique case of a PG-like lesion related to small vessel vasculitis in a 47-year-old man. Following the initiation of methotrexate (Methotrexate) therapy, the patient’s lesions improved significantly, highlighting the importance of recognizing PG-like lesions associated with vasculitis.